SLC6A3 antibody (C-Term)

Catalog No. ABIN6656084

Product Details anti-SLC6A3 Antibody

Target: SLC6A3 (Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3 (SLC6A3))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC6A3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse (Murine), Non-Human Primate

Cross-Reactivity (Details): Cross reactivity with Dopamine Transporter from other species has not been determined.

Purification: Anti-Dopamine Transporter antibody is directed against human dopamine transporter. Anti-Dopamine Transporter antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Anti-Dopamine Transporter antibody recognizes Dopamine Transporter from human, mouse and NHP sources.

Immunogen:

Immunogen: Anti-Dopamine Transporter Antibody was produced in rabbit by repeated immunizations with the synthetic peptide corresponding to the intracellular C-terminal region conjugated to KLH.

Immunogen Type: Peptide

Isotype: IgG

Application Details

Application Notes:

Immunohistochemistry Dilution: 1:1000

Application Note: Anti-Dopamine Transporter Antibody is suitable for use in ELISA, Western Blotting and IHC. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 88 kDa corresponding to DAT proteins in the appropriate cell lysate or extract.

ELISA Dilution: 1:10,000

Western Blot Dilution: 1:1000

Other Performance Data: enough antibody in each unit for 10 mini-western blots at suggested dilution

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Target Details for SLC6A3

Target: SLC6A3 (Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3 (SLC6A3))

Alternative Name: Dopamine Transporter (SLC6A3 Products)

Synonyms: DAT antibody, SLC6A3 antibody, Dat1 antibody, DAT1 antibody, PKDYS antibody, solute carrier family 6 member 3 antibody, solute carrier family 6 (neurotransmitter transporter), member 3 antibody, Sodium-dependent dopamine transporter antibody, solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 antibody, SLC6A3 antibody, slc6a3 antibody, dat-1 antibody, Slc6a3 antibody

Background:

Synonyms: Sodium-dependent dopamine transporter, DA transporter, DAT, Solute carrier family 6 member 3

Background: Dopamine Transporter Antibody detects dopamine transporter (DAT) which is responsible for the reaccumulation of dopamine after it has been released. DAT antibodies and antibodies for other markers of catecholamine biosynthesis are widely used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse. Levels of DAT protein expression are altered by chronic drug administration. Anti-Dopamine Transporter Antibody is ideal for investigators involved in Neuroscience.

Gene Name: SLC6A3

Gene ID: 6531

NCBI Accession: NP_001035

UniProt: Q01959

Pathways: Dopaminergic Neurogenesis