ITGA4 antibody (PE-Cy5)
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- Target See all ITGA4 Antibodies
- ITGA4 (Integrin alpha 4 (ITGA4))
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Reactivity
- Human, Mouse, Rat, Cow
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ITGA4 antibody is conjugated to PE-Cy5
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Application
- Flow Cytometry (FACS), Western Blotting (WB)
- Cross-Reactivity
- Human, Mouse, Rabbit
- Predicted Reactivity
- Rat,Cow,Horse
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Integrin alpha 4
- Isotype
- IgG
- Top Product
- Discover our top product ITGA4 Primary Antibody
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- Application Notes
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FCM(1:100-500)
Optimal working dilution should be determined by the investigator. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- ITGA4 (Integrin alpha 4 (ITGA4))
- Alternative Name
- Integrin alpha 4/CD49d (ITGA4 Products)
- Synonyms
- CD49D antibody, IA4 antibody, LOC100219853 antibody, integrin subunit alpha 4 antibody, integrin alpha 4 antibody, integrin subunit alpha 4 S homeolog antibody, ITGA4 antibody, Itga4 antibody, itga4.S antibody
- Background
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Synonyms: IA4, CD49D, Integrin alpha-4, CD49 antigen-like family member D, Integrin alpha-IV, VLA-4 subunit alpha, ITGA4
Background: Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells.
- Molecular Weight
- 150kDa
- Gene ID
- 3676
- UniProt
- P13612
- Pathways
- Integrin Complex
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