IL5 antibody (Interleukin 5) (APC)

Details for Product anti-IL5 Antibody No. ABIN6728660
Antigen
  • EDF
  • IL-5
  • TRF
  • Il-5
  • IL5
  • interleukin 5
  • IL5
  • Il5
Reactivity
Human
137
86
40
10
6
5
4
4
4
2
2
2
2
1
1
Host
Rat
121
60
30
2
Clonality (Clone)
Monoclonal ()
Conjugate
This IL5 antibody is conjugated to APC
35
7
3
3
3
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
143
119
44
32
26
23
21
19
19
16
13
11
9
5
5
5
3
3
2
2
1
Options
Clone TRFK5
Isotype IgG1, kappa
Plasmids, Primers & others Plasmids, Primers & others IL5 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name / IL-5 (IL5 Antibody Abstract)
Background

Synonyms: Interleukin-5,IL-5,B-cell differentiation factor I,T-cell replacing factor,TRF

Background: IL-5 is a homodimeric, disulphide-linked protein produced by T-cells. Monomeric human IL-5 is a 126 amino acid protein with a reported molecular weight of 26 kD for the homodimeric protein. Mouse and human IL-5 are approximately 70 % identical. IL-5 has been shown to promote the growth of immature hematopoietic BFU-E progenitors, stimulate the activation and differentiation of eosinophils, and promote the generation of cytotoxic lymphocytes. Mouse IL-5 induces the differentiation and proliferation of pre-activated B-cells and stimulates the production and secretion of IgM and IgA by B-cells stimulated with bacterial endotoxin. The TRFK5 antibody can neutralize the bioactivity of natural or recombinant IL-5.

Gene ID 3567, 16191
UniProt P05113, P04401
Pathways JAK-STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer PBS with 0.05 % Proclin300, 1 % BSA
Preservative ProClin
Precaution of Use This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
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