HGF antibody

Catalog No. ABIN6937376

This Mouse Monoclonal antibody specifically detects HGF in ELISA and Coat. It exhibits reactivity toward Human.

Quick Overview for HGF antibody (ABIN6937376)

Target: HGF (Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HGF antibody is un-conjugated

Application: ELISA, Coating (Coat)

Clone: EGH2 4C12-1

Product Details anti-HGF Antibody

Specificity: This gene encodes a protein that binds to the hepatocyte growth factor receptor to regulate cell growth, cell motility and morphogenesis in numerous cell and tissue types. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate alpha and beta chains, which form the mature heterodimer. This protein is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. This protein also plays a role in angiogenesis, tumorogenesis, and tissue regeneration. Although the encoded protein is a member of the peptidase S1 family of serine proteases, it lacks peptidase activity. Mutations in this gene are associated with nonsyndromic hearing loss.

Cross-Reactivity (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full-length human HGF/SF protein.

Isotype: IgG2b kappa

Application Details

Application Notes:

Known_Application: ELISA (For coating, order antibody without BSA),Optimal dilution for a specific application should be determined.

Positive_Control: HGF lysate.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for HGF

Target: HGF (Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF))

Alternative Name: HGF

Background: F-TCF, Fibroblast derived tumor cytotoxic factor, Hepatocyte growth factor (hepapoietin A, scatter factor), Hepatocyte growth factor beta chain, Hepatopoietin-A, HGF, HGFB, HPTA, Lung fibroblast derived mitogen, Scatter Factor,HGF / SF
Cellular localisation: Cytoplasmic

Molecular Weight: 91/64/34kDa precursor//

Gene ID: 3082, 396530, 561679

UniProt: P14210

Pathways: RTK Signaling, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor