BRD2 antibody

Catalog No. ABIN6942292

Product Details anti-BRD2 Antibody

Target: BRD2 (Bromodomain Containing 2 (BRD2))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This BRD2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: Recombinant protein within human BRD2 aa 1-200.

Clone: 6B5

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for BRD2

Target: BRD2 (Bromodomain Containing 2 (BRD2))

Alternative Name: BRD2 (BRD2 Products)

Synonyms: D6S113E antibody, FSH antibody, FSRG1 antibody, NAT antibody, RING3 antibody, RNF3 antibody, AW228947 antibody, D17H6S113E antibody, Frg-1 antibody, Fsrg-1 antibody, Fsrg1 antibody, Nat antibody, Ring3 antibody, Rnf3 antibody, mKIAA4005 antibody, brd2-a antibody, fsh antibody, fsrg1 antibody, nat antibody, ring3 antibody, rnf3 antibody, brd2 antibody, fe47f02 antibody, fi85h05 antibody, wu:fe47f02 antibody, wu:fi85h05 antibody, Ring3 protein antibody, bromodomain containing 2 antibody, bromodomain containing 2 S homeolog antibody, bromodomain containing 2a antibody, CHLREDRAFT_190116 antibody, CHLREDRAFT_150233 antibody, CHLREDRAFT_182576 antibody, CHLREDRAFT_188250 antibody, BRD2 antibody, Brd2 antibody, brd2.S antibody, brd2a antibody

Background:

Synonyms: Bromodomain-containing protein 2, O27.1.1, Really interesting new gene 3 protein, BRD2, KIAA9001, RING3

Background: The bromodomain-containing proteins include BRD2, BRD3, BRD4 and BRDT. BRD2 (RING3 protein) is a mitogen-activated nuclear protein whose gene is located in the human MHC II region, suggesting its relation to HLA-associated diseases. The bromodomain-containing proteins are ubiquitously expressed. BRD2 may play a role in spermatogenesis or folliculogenesis (By similarity). BRD2 binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly.

Gene ID: 6046

UniProt: P25440

Pathways: Chromatin Binding, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection