Dynamin 1-Like antibody (pSer616) (Biotin)

Catalog No. ABIN6943119

Product Details anti-Dynamin 1-Like Antibody (Biotin)

Target: Dynamin 1-Like (DNM1L)

Binding Specificity: pSer616

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dynamin 1-Like antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Pig,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthesised phosphopeptide derived from human DRP1 around the phosphorylation site of Ser616

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for Dynamin 1-Like

Target: Dynamin 1-Like (DNM1L)

Alternative Name: DRP1 (DNM1L Products)

Synonyms: DLP1 antibody, DRP1 antibody, DVLP antibody, DYMPLE antibody, EMPF antibody, HDYNIV antibody, 6330417M19Rik antibody, AI450666 antibody, Dlp1 antibody, Dnmlp1 antibody, Drp1 antibody, python antibody, Dnml1 antibody, dnm1l antibody, MGC53850 antibody, zgc:66163 antibody, DNM1L antibody, 18.m06247 antibody, CG3210 antibody, DRP antibody, Dmel\CG3210 antibody, Dnm1/Drp1 antibody, Drp antibody, Drp-1 antibody, drp-1 antibody, drp1 antibody, frat antibody, l(2)22Fc antibody, l(2)22Fd antibody, l(2)ND2 antibody, l(2)ND3 antibody, dynamin 1 like antibody, dynamin 1-like antibody, dynamin 1-like L homeolog antibody, dynamin-1-like antibody, dynamin-1-like protein antibody, dynamin-like protein antibody, Dynamin related protein 1 antibody, DNM1L antibody, Dnm1l antibody, dnm1l.L antibody, dnm1l antibody, LOC100369408 antibody, LOC411472 antibody, dyn1 antibody, cgd1_580 antibody, EHI_052740 antibody, PVX_092875 antibody, BBOV_II002980 antibody, Drp1 antibody

Background:

Synonyms: DRP1 (phospho S616), p-DRP1 (phospho S616), P-DRP1 (Ser616), DLP1, dnm1l, DNM1L_HUMAN, Dnm1p/Vps1p-like protein, DVLP, Dymple, Dynamin 1 like, Dynamin family member proline-rich carboxyl-terminal domain less, Dynamin like protein, Dynamin related protein 1, Dynamin-1-like protein, Dynamin-like protein 4, Dynamin-like protein, Dynamin-like protein IV, Dynamin-related protein 1, DYNIV 11, FLJ41912, HdynIV, VPS1.

Background: This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013]

Gene ID: 10059

UniProt: O00429