IL13 Receptor alpha 1 antibody

Catalog No. ABIN6943798

Product Details anti-IL13 Receptor alpha 1 Antibody

Target: IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This IL13 Receptor alpha 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: Synthetic peptide corresponding to residues in the extracellular domain of Human IL13 receptor alpha 1

Clone: 1C1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for IL13 Receptor alpha 1

Target: IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))

Alternative Name: IL13RA1 (IL13RA1 Products)

Synonyms: CD213A2 antibody, CT19 antibody, IL-13R antibody, IL13BP antibody, CD213A1 antibody, IL-13Ra antibody, NR4 antibody, AI882074 antibody, CD213a1 antibody, IL-13r[a] antibody, Il13ra antibody, IL13RA1 antibody, il-13ra1 antibody, si:ch211-150g2.2 antibody, interleukin 13 receptor subunit alpha 2 antibody, interleukin 13 receptor subunit alpha 1 antibody, interleukin 13 receptor, alpha 1 antibody, interleukin 13 receptor, alpha 1-like antibody, IL13RA2 antibody, IL13RA1 antibody, Il13ra1 antibody, il13ra1 antibody, LOC100360218 antibody

Background:

Synonyms: Interleukin-13 receptor subunit alpha-1, Cancer/testis antigen 19, CD213a1, IL-13 receptor subunit alpha-1, IL-13R subunit alpha-1, IL-13R-alpha-1, IL-13RA1, CT19, IL13RA1, IL13R, IL13RA.

Background: Interleukin 13 receptor, alpha 1, also known as IL13RA1 and CD213A1 (cluster of differentiation 213A1), is a human gene. Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.

Gene ID: 3597

UniProt: P78552

Pathways: JAK-STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response