MARK3 antibody

Catalog No. ABIN6944028

Product Details anti-MARK3 Antibody

Target: MARK3 (MAP/microtubule Affinity-Regulating Kinase 3 (MARK3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MARK3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: Recombinant protein within human Mark3 aa 600-750.

Clone: 2F7

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200
IP(1-2 μg)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for MARK3

Target: MARK3 (MAP/microtubule Affinity-Regulating Kinase 3 (MARK3))

Alternative Name: MARK3 (MARK3 Products)

Synonyms: MARK3 antibody, par1 antibody, par-1 antibody, Par-1A antibody, CTAK1 antibody, KP78 antibody, PAR1A antibody, Par-1a antibody, 1600015G02Rik antibody, A430080F22Rik antibody, C-TAK1 antibody, ETK-1 antibody, ETK1 antibody, Emk2 antibody, MPK10 antibody, fi39g08 antibody, wu:fi39g08 antibody, zgc:152848 antibody, zgc:55693 antibody, c-tak1 antibody, ctak1 antibody, emk-2 antibody, microtubule affinity regulating kinase 3 antibody, MAP/microtubule affinity-regulating kinase 3b antibody, MAP/microtubule affinity regulating kinase 3 antibody, MAP/microtubule affinity-regulating kinase 3a antibody, microtubule affinity regulating kinase 3 L homeolog antibody, MARK3 antibody, mark3b antibody, mark3 antibody, Mark3 antibody, mark3a antibody, mark3.L antibody

Background:

Synonyms: MAP/microtubule affinity-regulating kinase 3, C-TAK1, cTAK1, Cdc25C-associated protein kinase 1, ELKL motif kinase 2, EMK-2, Protein kinase STK10, Ser/Thr protein kinase PAR-1, Par-1a, Serine/threonine-protein kinase p78, microtubule affinity regulating kinase 3

Background: Serine/threonine-protein kinase. Involved in the specific phosphorylation of microtubule-associated proteins for MAP2 and MAP4. Phosphorylates the microtubule-associated protein MAPT/TAU. Phosphorylates CDC25C on 'Ser-216'. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus. Negatively regulates the Hippo signaling pathway and antagonizes the phosphorylation of LATS1. Cooperates with DLG5 to inhibit the kinase activity of STK3/MST2 toward LATS1.

Gene ID: 4140

UniProt: P27448

Pathways: SARS-CoV-2 Protein Interactome