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Nicastrin antibody

NCSTN Reactivity: Human WB Host: Rabbit Monoclonal 3F10 unconjugated

Catalog No. ABIN6944227

Datasheet as PDF

Target See all Nicastrin (NCSTN) Antibodies

Nicastrin (NCSTN)
Reactivity
37

33

22

6

6

5

1

1
Human
Host
51

2
Rabbit
Compatible Secondaries
Clonality
44

9
Monoclonal
Conjugate
20

3

3

3

3

3

3

3

1

1

1

1

1

1

1

1

1

1

1

1
This Nicastrin antibody is un-conjugated
Application
39

13

13

9

7

4

4

3

3

2

2
Western Blotting (WB)

Cross-Reactivity

Human

Purification

Purified by Protein A.

Immunogen

Synthetic peptide within Human Nicastrin aa 650-750 (C terminal).

Clone

3F10

Isotype

IgG

Top Product

Discover our top product NCSTN Primary Antibody
anti-Nicastrin (NCSTN) (AA 16-115) antibody
NCSTN Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated

anti-Nicastrin (NCSTN) (AA 429-669) antibody
NCSTN Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated

anti-Nicastrin (NCSTN) (AA 21-120) antibody
NCSTN Reactivity: Mouse WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-Nicastrin (NCSTN) (C-Term) antibody
NCSTN Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Nicastrin (NCSTN) (AA 99-133) antibody
NCSTN Reactivity: Human, Rat WB Host: Rabbit Polyclonal RB53031 unconjugated

anti-Nicastrin (NCSTN) (AA 1-689) antibody
NCSTN Reactivity: Human WB Host: Rabbit Polyclonal unconjugated

anti-Nicastrin (NCSTN) (AA 16-115) antibody
NCSTN Reactivity: Human WB, ELISA Host: Mouse Monoclonal 1E8 unconjugated

anti-Nicastrin (NCSTN) (AA 420-655) antibody
NCSTN Reactivity: Human WB, IHC, ICC Host: Rabbit Polyclonal unconjugated

anti-Nicastrin (NCSTN) (AA 35-534) antibody
NCSTN Reactivity: Rat WB, IHC, ICC Host: Rabbit Polyclonal unconjugated

anti-Nicastrin (NCSTN) (N-Term) antibody
NCSTN Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated

Application Notes

WB 1:300-5000

Restrictions

For Research Use only
Format

Liquid

Concentration

1 μg/μL

Buffer

Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative

ProClin

Precaution of Use

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage

4 °C,-20 °C

Storage Comment

Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Expiry Date

12 months
Target

Nicastrin (NCSTN)

Alternative Name

NCSTN (NCSTN Products)

Synonyms

CG7012 antibody, Dmel\\CG7012 antibody, Nct antibody, Nic antibody, S5A antibody, ST96B antibody, agro antibody, dNct antibody, nic antibody, NCSTN antibody, DKFZp469O2418 antibody, APH2 antibody, 9430068N19Rik antibody, AA727311 antibody, Aph2 antibody, D1Dau13e antibody, Kiaa0253 antibody, mKIAA0253 antibody, nicastrin antibody, Nicastrin antibody, NCSTN antibody, nct antibody, ncstn antibody, CpipJ_CPIJ001617 antibody, Ncstn antibody, aph-2 antibody

Background

Synonyms: Nicastrin, NCSTN, KIAA0253, ATAG1874
Background: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.

Gene ID

23385

UniProt

Q92542

Pathways

Notch Signaling, Neurotrophin Signaling Pathway