Tumor Protein p73 antibody (Tumor Protein P73)

Details for Product anti-TP73 Antibody No. ABIN6944402
Target
Reactivity
Human, Mouse
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Host
Rabbit
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Clonality (Clone)
Monoclonal ()
Conjugate
This Tumor Protein p73 antibody is un-conjugated
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Application
Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Options
Immunogen Human p73 between 50-150 amino acids
Clone 2B11
Isotype IgG
Purification Purified by Protein A.
Target
Alternative Name p73 (TP73 Antibody Abstract)
Background

Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. Maybe a tumor suppressor protein.


Synonyms: Tumor protein p73, p53-like transcription factor, p53-related protein, TP73, P73
Gene ID 7161
UniProt O15350
Pathways Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus
Application Notes WB(1:300-1000), IHC-P(1:200-400), IF(ICC)(1:50-200)
Restrictions For Research Use only
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months