CD80 antibody

Catalog No. ABIN6961451

Product Details anti-CD80 Antibody

Target: CD80

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD80 antibody is un-conjugated

Application: Flow Cytometry (FACS), Functional Studies (Func)

Cross-Reactivity: Rhesus Monkey

Purification: This monoclonal antibody preparation was purified from tissue culture supernatant via affinity chromatography. For In Vivo Ready™ (IVR) products, each preparation is also evaluated for endotoxin levels using the LAL assay. It is recommended to store the product undiluted at 4°C. Do not freeze.

Endotoxin Level: Low endotoxin: < 0.01 EU/ug

Clone: 2D10-4

Isotype: IgG1 kappa

Application Details

Comment:

2.0 mg/mL

Restrictions: For Research Use only

Handling

Buffer: 10 mM NaH2PO4, 150 mM NaCl, pH 7.2

Preservative: Azide free

Storage: 4 °C

Storage Comment: 2-8°C

Expiry Date: 12 months

Target Details for CD80

Target: CD80

Alternative Name: CD80 (B7-1) (CD80 Products)

Synonyms: B7 antibody, B7-1 antibody, B7.1 antibody, BB1 antibody, CD28LG antibody, CD28LG1 antibody, LAB7 antibody, B71 antibody, Cd28l antibody, Ly-53 antibody, Ly53 antibody, MIC17 antibody, TSA1 antibody, CD80 molecule antibody, Cd80 molecule antibody, CD80 antigen antibody, CD80 antibody, Cd80 antibody

Background: The 2D10.4 antibody reacts with human CD80, a 60 kDa glycoprotein that is a member of the Ig superfamily. CD80, also known as B7-1, is a ligand for the T cell receptors CD28 and CTLA-4 (CD152). Along with CD86, CD80 plays a major role in regulating the activation of T cells. CD80 is expressed by activated antigen presenting cells including B cells, macrophages, and dendritic cells.

Gene ID: 941

UniProt: P33681

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints