CBX1 antibody
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- Target See all CBX1 Antibodies
- CBX1 (Chromobox Homolog 1 (CBX1))
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Reactivity
- Human, Mouse
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CBX1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP)
- Characteristics
- HP1 beta (Heterochromatin Protein 1 beta, Chromobox protein 1, CBX1) is one of the mammalian homologues of Drosophila HP1, first identified through its role in the maintenance of regions of the genome in a heterochromatic state. HP1 beta contains a chromo domain and a chromo shadow domain. Through the chromo domain, HP1 proteins are recruited to regions of chromatin that exhibit methylation of lysine 9 of histone H3. Interaction between HP1 beta and the lamin B receptor can facilitate the sequestration of heterochromatin to the nuclear envelope. HP1b antibody (mAb) (Clone 1MOD-1A9) was raised in a Mouse host. It has been validated for use in Immunocytochemistry, Immunofluorescence, Immunoprecipitation and Western blot, it has been shown to react with Human and Mouse samples.
- Purification
- Protein A Chromatography
- Immunogen
- This HP1β antibody was raised against recombinant mouse HP1β.
- Clone
- 1MOD-1A9
- Isotype
- IgG1
- Top Product
- Discover our top product CBX1 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- Purified IgG in 60 mM Sodium Citrate, 105 mM Tris-HCl, 30 % glycerol, and 0.035 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- Target
- CBX1 (Chromobox Homolog 1 (CBX1))
- Alternative Name
- HP1beta (CBX1 Products)
- Synonyms
- CBX antibody, HP1-BETA antibody, HP1Hs-beta antibody, HP1Hsbeta antibody, M31 antibody, MOD1 antibody, p25beta antibody, Cbx antibody, Cbx-rs2 antibody, E430007M08Rik antibody, HP1B antibody, Hp1beta antibody, cbx1 antibody, wu:fe14b09 antibody, zgc:55739 antibody, zgc:86924 antibody, chromobox 1 antibody, chromobox homolog 1a (HP1 beta homolog Drosophila) antibody, chromobox 1 S homeolog antibody, chromobox homolog 1b (HP1 beta homolog Drosophila) antibody, CBX1 antibody, Cbx1 antibody, cbx1a antibody, cbx1.S antibody, cbx1b antibody
- Molecular Weight
- 25 kDa
- NCBI Accession
- NP_006798
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