PSMD14 antibody (AA 331-718)

Catalog No. ABIN6972301

Product Details anti-PSMD14 Antibody

Target: PSMD14 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 14 (PSMD14))

Binding Specificity: AA 331-718

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This PSMD14 antibody is un-conjugated

Application: Immunofluorescence (IF), Immunocytochemistry (ICC)

Characteristics: MAD1 (MAD1L1, Mitotic arrest deficient 1) is a component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD1 homoderizes with MAD2L1 and is present at the kinetochore. Defects in MAD1 are involved in the development and/or progression of various types of cancer. MAD1 antibody (mAb) (Clone 9B10) was raised in a Mouse host. It has been validated for use in Immunocytochemistry and Immunofluorescence, it has been shown to react with Human and Mouse samples.

Purification: Protein G Chromatography

Immunogen: This MAD1 antibody was raised against a peptide corresponding to amino acids 331-718 of mouse MAD1.

Clone: 9B10

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Target Details for PSMD14

Target: PSMD14 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 14 (PSMD14))

Alternative Name: MAD1 (PSMD14 Products)

Synonyms: PAD1 antibody, POH1 antibody, RPN11 antibody, 2610312C03Rik antibody, 3200001M20Rik antibody, AA986732 antibody, Pad1 antibody, Poh1 antibody, rpm11 antibody, zgc:162272 antibody, proteasome 26S subunit, non-ATPase 14 antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 antibody, 26S proteasome non-ATPase regulatory subunit 14 antibody, proteasome 26S subunit, non-ATPase 14 L homeolog antibody, 26S proteasome-associated pad1 homolog antibody, PSMD14 antibody, Psmd14 antibody, rpn-11 antibody, psmd14 antibody, psmd14.L antibody

Molecular Weight: 85 kDa

NCBI Accession: NP_034882

Pathways: Mitotic G1-G1/S Phases, DNA Replication, M Phase, Positive Regulation of Endopeptidase Activity, Synthesis of DNA, Ubiquitin Proteasome Pathway