SPINK5 antibody (AA 21-120) (Alexa Fluor 680)

Catalog No. ABIN6980987

Product Details anti-SPINK5 Antibody (Alexa Fluor 680)

Target: SPINK5 (serine Peptidase Inhibitor, Kazal Type 5 (SPINK5))

Binding Specificity: AA 21-120

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPINK5 antibody is conjugated to Alexa Fluor 680

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human

Predicted Reactivity: Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SPINK5/LEKTI

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SPINK5

Target: SPINK5 (serine Peptidase Inhibitor, Kazal Type 5 (SPINK5))

Alternative Name: SPINK5/LEKTI (SPINK5 Products)

Synonyms: LEKTI antibody, LETKI antibody, NETS antibody, NS antibody, VAKTI antibody, 2310065D10Rik antibody, AV238912 antibody, LEKT1 antibody, LETK1 antibody, VAKT1 antibody, serine peptidase inhibitor, Kazal type 5 antibody, Spink5 antibody, SPINK5 antibody

Background:

Synonyms: Hemofiltrate peptide HF7665, ISK5_HUMAN, LEKTI, Lympho-epithelial Kazal-type-related inhibitor, Lymphoepithelial Kazal type related inhibitor, NETS, NS, Serine peptidase inhibitor Kazal type 5, SPINK5, VAKTI.

Background: This gene encodes a multidomain serine protease inhibitor that contains 15 potential inhibitory domains. The inhibitor may play a role in skin and hair morphogenesis and anti-inflammatory and/or antimicrobial protection of mucous epithelia. Mutations may result in Netherton syndrome, a disorder characterized by ichthyosis, defective cornification, and atopy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Gene ID: 11005

UniProt: Q9NQ38