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SLC9A1 antibody (C-Term)

SLC9A1 Reactivity: Human, Rat, Mouse WB, ELISA, IHC (p), IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6990817
  • Target See all SLC9A1 Antibodies
    SLC9A1 (Solute Carrier Family 9, Subfamily A (NHE1, Cation Proton Antiporter 1), Member 1 (SLC9A1))
    Binding Specificity
    • 15
    • 7
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 34
    • 33
    • 24
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 39
    • 4
    • 2
    Rabbit
    Clonality
    • 41
    • 4
    Polyclonal
    Conjugate
    • 19
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SLC9A1 antibody is un-conjugated
    Application
    • 35
    • 17
    • 13
    • 13
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Specificity
    At least three isoforms of Nhe-1 are known to exist.
    Purification
    Nhe-1 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    Nhe-1 antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of the human Nhe-1. The immunogen is located within the last 50 amino acids of Nhe-1.
    Isotype
    IgG
    Top Product
    Discover our top product SLC9A1 Primary Antibody
  • Application Notes
    Nhe-1 antibody can be used for detection of Nhe-1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Nhe-1 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    Nhe-1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    SLC9A1 (Solute Carrier Family 9, Subfamily A (NHE1, Cation Proton Antiporter 1), Member 1 (SLC9A1))
    Alternative Name
    Nhe-1 (SLC9A1 Products)
    Synonyms
    AT-NHX1 antibody, ATNHX antibody, ATNHX1 antibody, NA(+)/H(+) ANTIPORTER antibody, Na+/H+ exchanger 1 antibody, T21B4.60 antibody, T21B4_60 antibody, AW554487 antibody, Apnh antibody, Nhe1 antibody, swe antibody, NHE-1 antibody, NHE1 antibody, APNH antibody, Na+/H+ exchanger 1 antibody, solute carrier family 9 (sodium/hydrogen exchanger), member 1 antibody, solute carrier family 9 member A1 antibody, NHX1 antibody, Slc9a1 antibody, SLC9A1 antibody
    Background
    Nhe-1 Antibody: The Na+/H+ antiporter (Nhe-1) is a ubiquitous membrane-bound enzyme involved in pH regulation of vertebrate cells and is specifically inhibited by the diuretic drug amiloride and activated by a variety of signals including growth factors, mitogens, neurotransmitters, and tumor promoters. Nhe-1 acts as an anchor for actin filaments to control the integrity of the cortical cytoskeleton. This occurs through a previously unrecognized structural link between Nhe-1 and the actin-binding proteins ezrin, radixin, and moesin, collectively referred to as ERM proteins. A structural role for Nhe-1 has been proposed in regulating the cortical cytoskeleton that is independent of its function as an ion exchanger. It is also thought that Nhe-1 play a role in hypertension.
    Molecular Weight
    Predicted: 52, 90 kDa

    Observed: 50, 90 kDa
    Gene ID
    6548
    UniProt
    P19634
    Pathways
    Glycosaminoglycan Metabolic Process, Proton Transport
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