Prostaglandin D2 Receptor 2 (PTGDR2) (AA 320-370) antibody
-
- Target See all Prostaglandin D2 Receptor 2 (PTGDR2) Antibodies
- Prostaglandin D2 Receptor 2 (PTGDR2)
-
Binding Specificity
- AA 320-370
-
Reactivity
- Human, Mouse
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- Un-conjugated
-
Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- Purification
- PTGDR2 Antibody is affinity chromatography purified via peptide column.
- Immunogen
- Rabbit polyclonal PTGDR2 antibody was raised against a 19 amino acid peptide near the center of human PTGDR2. The immunogen is located within amino acids 320 - 370 of PTGDR2.
- Isotype
- IgG
- Top Product
- Discover our top product PTGDR2 Primary Antibody
-
-
- Application Notes
-
PTGDR2 antibody can be used for detection of PTGDR2 by Western blot at 0.5 - 1 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PTGDR2 Antibody is supplied in PBS containing 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,4 °C
- Storage Comment
- PTGDR2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
-
- Target
- Prostaglandin D2 Receptor 2 (PTGDR2)
- Alternative Name
- PTGDR2 (PTGDR2 Products)
- Synonyms
- CD294 antibody, CRTH2 antibody, DL1R antibody, DP2 antibody, GPR44 antibody, Crth2 antibody, Grp45 antibody, Ptgdr2 antibody, Gpr44 antibody, prostaglandin D2 receptor 2 antibody, PTGDR2 antibody, Ptgdr2 antibody
- Background
- PTGDR2 Antibody: The prostaglandin D2 receptor 2 (PTGDR2), also known as CRTH2, is expressed on Th2 cells and eosinophils and mediates chemotaxis of these cells to PGD2 and is thus thought to be a key receptor mediating eosinophil and Th2 recruitment during allergic responses. However, PTGDR2-null mice showed enhanced eosinophil recruitment into the lung consistent with observations that the PTGDR2-null mice produced significantly higher amounts of interleukin-5 (IL-5) and IL-3. This suggests that PTGDR2 plays a nonredundant role in restricting eosinophilia and allergic response in vivo.
- Molecular Weight
- Predicted: 43 kDa
- Gene ID
- 11251
- NCBI Accession
- NP_004769
- UniProt
- Q9Y5Y4
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling
-