IL-6 antibody
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- Target See all IL-6 (IL6) Antibodies
- IL-6 (IL6) (Interleukin 6 (IL6))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IL-6 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Characteristics
- Polyclonal Antibody
- Purification
- Antigen affinity purification
- Immunogen
- Synthetic peptide of human IL6
- Isotype
- IgG
- Top Product
- Discover our top product IL6 Primary Antibody
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- Application Notes
- WB 1:500-1:2000, ELISA 1:5000-1:10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.1 mg/mL
- Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- IL-6 (IL6) (Interleukin 6 (IL6))
- Alternative Name
- IL6 (IL6 Products)
- Synonyms
- BSF2 antibody, HGF antibody, HSF antibody, IFNB2 antibody, IL-6 antibody, Il-6 antibody, ILg6 antibody, Ifnb2 antibody, il6 antibody, CHIL-6 antibody, interleukin 6 antibody, interleukin-6 antibody, IL6 antibody, Il6 antibody, il-6 antibody, IL-6 antibody
- Background
- Interleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. IL-6 Plays an essential role in the final differentiation of B-cells into Ig-secreting cells involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells,T-cells,hepatocytes,hematopoietic progenitor cells and cells of the CNS. IL-6 is also considered a myokine,a cytokine produced from muscle,and is elevated in response to muscle contraction. IL-6 has been shown to interact with interleukin-6 receptor and glycoprotein 130. Additionally,IL-6 is involved in hematopoiesis,bone metabolism,and cancer progression,and has been defined an essential role in directing transition from innate to acquired immunity.
- Molecular Weight
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Observed_MW: Refer to figures
Calculated_MW: 24 kDa
- UniProt
- P05231
- Pathways
- TLR Signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
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