PKC zeta antibody
-
- Target See all PKC zeta (PRKCZ) Antibodies
- PKC zeta (PRKCZ) (Protein Kinase C, zeta (PRKCZ))
-
Reactivity
- Human, Mouse, Rat, Monkey
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This PKC zeta antibody is un-conjugated
-
Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Synthesized peptide derived from human PKC zeta around the non-phosphorylation site of Thr560.
- Isotype
- IgG
- Top Product
- Discover our top product PRKCZ Primary Antibody
-
-
- Application Notes
- WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- PKC zeta (PRKCZ) (Protein Kinase C, zeta (PRKCZ))
- Alternative Name
- PKC zeta (PRKCZ Products)
- Synonyms
- TPKC antibody, PKCzeta antibody, prkcz-A antibody, pkc-zeta antibody, PRKCZ antibody, pkc2 antibody, PKC-ZETA antibody, PKC2 antibody, AI098070 antibody, C80388 antibody, Pkcz antibody, R74924 antibody, aPKCzeta antibody, zetaPKC antibody, 14-3-3-zetaisoform antibody, r14-3-3 antibody, pkcz antibody, si:ch211-150o23.4 antibody, protein kinase C zeta L homeolog antibody, protein kinase C zeta antibody, protein kinase C, zeta antibody, prkcz.L antibody, PRKCZ antibody, prkcz antibody, Prkcz antibody
- Background
- This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Phosphorylates 'Ser-311' of RELA subunit of NF-kappa-B.PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. Subunit of a quaternary complex that plays a central role in epithelial cell polarization.
- Molecular Weight
-
Observed_MW: 80 kDa
Calculated_MW: 68 kDa
- UniProt
- Q05513
- Pathways
- NF-kappaB Signaling, RTK Signaling, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
-