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Leptin Receptor antibody

LEPR Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7254277
  • Target See all Leptin Receptor (LEPR) Antibodies
    Leptin Receptor (LEPR)
    Reactivity
    • 108
    • 71
    • 49
    • 19
    • 12
    • 4
    • 3
    • 3
    Human
    Host
    • 111
    • 14
    • 2
    • 2
    • 1
    • 1
    Rabbit
    Clonality
    • 108
    • 23
    Polyclonal
    Conjugate
    • 49
    • 11
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This Leptin Receptor antibody is un-conjugated
    Application
    • 82
    • 42
    • 36
    • 35
    • 26
    • 25
    • 16
    • 11
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Antigen affinity purification
    Immunogen
    Synthetic peptide of human LEPR
    Isotype
    IgG
    Top Product
    Discover our top product LEPR Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.84 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Leptin Receptor (LEPR)
    Alternative Name
    LEPR (LEPR Products)
    Synonyms
    CD295 antibody, LEP-R antibody, LEPRD antibody, OB-R antibody, OBR antibody, obr antibody, cd295 antibody, ob-rb antibody, Fa antibody, LEPROT antibody, Leprb antibody, Modb1 antibody, OB-RGRP antibody, Obr antibody, db antibody, diabetes antibody, obese-like antibody, obl antibody, ObRb antibody, Ob-R antibody, Ob-RM antibody, lepr antibody, leptin receptor antibody, leptin receptor S homeolog antibody, LEPR antibody, lepr antibody, Lepr antibody, lepr.S antibody
    Background
    The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).
    Molecular Weight

    Observed_MW: Refer to figures

    Calculated_MW: 133 kDa

    UniProt
    P48357
    Pathways
    JAK-STAT Signaling, AMPK Signaling, Feeding Behaviour
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