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MBTPS1 antibody

MBTPS1 Reactivity: Human IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7256896
  • Target See all MBTPS1 Antibodies
    MBTPS1 (Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1))
    Reactivity
    • 28
    • 12
    • 11
    Human
    Host
    • 27
    • 1
    Rabbit
    Clonality
    • 27
    • 1
    Polyclonal
    Conjugate
    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MBTPS1 antibody is un-conjugated
    Application
    • 15
    • 9
    • 8
    • 6
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human MBTPS1 (NP_003782.1).
    Isotype
    IgG
  • Application Notes
    IHC 1:50-1:200 IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    MBTPS1 (Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1))
    Alternative Name
    MBTPS1 (MBTPS1 Products)
    Synonyms
    PCSK8 antibody, S1P antibody, SKI-1 antibody, 0610038M03Rik antibody, AV003995 antibody, Ski1 antibody, mKIAA0091 antibody, S1p antibody, Ski-1 antibody, membrane bound transcription factor peptidase, site 1 antibody, membrane-bound transcription factor peptidase, site 1 antibody, MBTPS1 antibody, Mbtps1 antibody
    Background
    This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction.
    Gene ID
    8720
    UniProt
    Q14703
    Pathways
    ER-Nucleus Signaling
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