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MTOR antibody (pSer2448)
mTOR
Reactivity: Human, Mouse, Rat
IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MTOR Antibody
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Target
See all MTOR (mTOR) Antibodies
MTOR (mTOR)
(Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))
Binding Specificity
All epitopes for MTOR antibodies
pSer2448
Reactivity
All reactivities for MTOR antibodies
Human, Mouse, Rat
Host
All hosts for MTOR antibodies
Rabbit
Clonality
All clonalities for MTOR antibodies
Polyclonal
Conjugate
All conjugates for MTOR antibodies
This MTOR antibody is un-conjugated
Application
All applications for MTOR antibodies
Immunofluorescence (IF)
Characteristics
Phosphorylated antibody
Purification
Affinity purification
Immunogen
A synthetic phosphorylated peptide around S2448 of human mTOR (NP_004949.1).
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
IF 1:50-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for MTOR
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Target
MTOR (mTOR)
(Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))
Alternative Name
mTOR (mTOR Products )
Synonyms
FRAP1 antibody, FRAP antibody, FRAP2 antibody, RAFT1 antibody, RAPT1 antibody, 2610315D21Rik antibody, AI327068 antibody, Frap1 antibody, flat antibody, frap1 antibody, tor antibody, wu:fc22h08 antibody, mechanistic target of rapamycin kinase antibody, mechanistic target of rapamycin antibody, mechanistic target of rapamycin (serine/threonine kinase) antibody, MTOR antibody, Mtor antibody, mtor antibody
Background
The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.
Gene ID
2475
UniProt
P42345
Pathways
PI3K-Akt Signaling , RTK Signaling , AMPK Signaling , Interferon-gamma Pathway , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Regulation of Actin Filament Polymerization , Regulation of Muscle Cell Differentiation , Regulation of Cell Size , Skeletal Muscle Fiber Development , Regulation of Carbohydrate Metabolic Process , Autophagy , CXCR4-mediated Signaling Events , BCR Signaling , Warburg Effect
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