CD80 antibody
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- Target See all CD80 Antibodies
- CD80
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Reactivity
- Mouse, Dog
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Host
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Armenian Hamster
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Clonality
- Monoclonal
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Conjugate
- This CD80 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
- Specificity
- The Armenian hamster monoclonal antibody 16-10A1 reacts with an extracellular epitope of CD80 (B7-1), a 60 kDa single chain type I glycoprotein of immunoglobulin supergene family, expressed on professional antigen-presenting cells, such as dendritic cells, macrophages or activated B lymphocytes.
- Purification
- Purified by protein-A affinity chromatography.
- Endotoxin Level
- Low Endotoxin
- Immunogen
- CD80-transfected CHO cell line
- Clone
- 16-10A1
- Isotype
- IgG2
- Top Product
- Discover our top product CD80 Primary Antibody
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anti-CD80 (CD80) (AA 35-288) antibody
CD80 Reactivity: Human FACS, WB, ELISA, IHC, ICC, Neut Host: Mouse Monoclonal 1G3D7 unconjugated
anti-CD80 (CD80) antibodyCD80 Reactivity: Mouse, Dog FACS, IP, IHC (fro) Host: Armenian Hamster Monoclonal 16-10A1 unconjugated
anti-CD80 (CD80) (AA 38-246) antibodyCD80 Reactivity: Mouse WB, IP, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-CD80 (CD80) (Extracellular Domain) antibodyCD80 Reactivity: Human FACS, IP Host: Mouse Monoclonal MEM-233 unconjugated
anti-CD80 (CD80) (AA 251-321) antibodyCD80 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p), ICC, IHC (fro), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated
anti-CD80 (CD80) (Extracellular Domain) antibody (FITC)CD80 Reactivity: Human FACS Host: Mouse Monoclonal MEM-233 FITC
anti-CD80 (CD80) antibodyCD80 Reactivity: Human ELISA, IHC, ICC Host: Mouse Monoclonal 2A2 unconjugated
anti-CD80 (CD80) (Extracellular Domain) antibody (PE)CD80 Reactivity: Human FACS Host: Mouse Monoclonal MEM-233 PE
anti-CD80 (CD80) (Extracellular Domain) antibody (APC)CD80 Reactivity: Human FACS Host: Mouse Monoclonal MEM-233 APC
anti-CD80 (CD80) (Extracellular Domain) antibody (PerCP)CD80 Reactivity: Human FACS Host: Mouse Monoclonal MEM-233 PerCP
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- Application Notes
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Flow cytometry: Recommended dilution: 1-4 μg/mL.
Functional application: Blocking. - Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4
- Preservative
- Azide free
- Storage
- 4 °C
- Storage Comment
- Store at 2-8°C. Do not freeze.
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- Target
- CD80
- Alternative Name
- CD80 (CD80 Products)
- Synonyms
- B7 antibody, B7-1 antibody, B7.1 antibody, BB1 antibody, CD28LG antibody, CD28LG1 antibody, LAB7 antibody, B71 antibody, Cd28l antibody, Ly-53 antibody, Ly53 antibody, MIC17 antibody, TSA1 antibody, CD80 molecule antibody, Cd80 molecule antibody, CD80 antigen antibody, CD80 antibody, Cd80 antibody
- Background
- CD80 Molecule,CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28 and of an inhibitory receptor CTLA-4 (CD152). The both B7 Molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, the both molecules can also substitute for each other in this process. The question what are the differences in CD80 and CD86 competency has not been fully elucidated yet, there are still conflicts in results about their respective roles in initiation or sustaining of the T cell immune response.,B7-1, BB1
- Gene ID
- 12519
- UniProt
- Q00609
- Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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