CRHR2 antibody (Extracellular, N-Term)

Catalog No. ABIN7043088

Product Details anti-CRHR2 Antibody

Target: CRHR2 (Corticotropin Releasing Hormone Receptor 2 (CRHR2))

Binding Specificity: AA 20-34, Extracellular, N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRHR2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Characteristics: Anti-CRF2/CRHR2 (extracellular) Antibody (ABIN7043088, ABIN7044188 and ABIN7044189)) is a highly specific antibody directed against an epitope of the rat Corticotropin-releasing factor receptor 2. The antibody can be used in western blot and indirect live cell flow cytometry applications. It has been designed to recognize CRHR2 from rat, mouse, and human samples.

Purification: Affinity purified on immobilized antigen.

Immunogen:

Immunogen: Synthetic peptide

Immunogen Sequence: (C)EELLLDGWGEPPDPE, corresponding to amino acid residues 20-34 of rat CRHR2

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.

Concentration: 0.8 mg/mL

Buffer: Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1 % BSA, 0.05 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: RT,4 °C,-20 °C

Storage Comment:

Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Target Details for CRHR2

Target: CRHR2 (Corticotropin Releasing Hormone Receptor 2 (CRHR2))

Alternative Name: CRF2/CRHR2 (CRHR2 Products)

Synonyms: CRF-RB antibody, CRF2 antibody, CRFR2 antibody, HM-CRF antibody, CRF-R2 antibody, CRFR2alpha antibody, CRFR2beta antibody, Crfr2 antibody, Crf2r antibody, CRH-R2 antibody, crhr2-A antibody, corticotropin releasing hormone receptor 2 antibody, corticotropin releasing hormone receptor 2 S homeolog antibody, CRHR2 antibody, Crhr2 antibody, crhr2.S antibody

Background: Alternative names: Corticotropin-releasing factor receptor 2, CRF-R-2, CRF2 receptor beta isoform, Corticotropin-releasing hormone receptor 2, CRH receptor 2 variant B

Gene ID: 64680

NCBI Accession: NM_001202475

UniProt: P47866

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Feeding Behaviour