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Recombinant CD25 antibody

IL2RA Reactivity: Human FACS, ELISA, BR Host: Rabbit Chimeric AHT107 unconjugated Recombinant Antibody
Catalog No. ABIN7072445
  • Target See all CD25 (IL2RA) Antibodies
    CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
    Antibody Type
    Recombinant Antibody
    Reactivity
    • 165
    • 99
    • 35
    • 9
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 126
    • 77
    • 70
    • 2
    • 1
    Rabbit
    Clonality
    • 197
    • 76
    • 1
    Chimeric
    Conjugate
    • 102
    • 29
    • 26
    • 23
    • 18
    • 9
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD25 antibody is un-conjugated
    Application
    • 190
    • 85
    • 50
    • 46
    • 38
    • 28
    • 19
    • 15
    • 14
    • 14
    • 8
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), ELISA, Blocking Reagent (BR)
    Characteristics

    Original Species of Ab: Mouse

    Original Format of Ab: IgG1

    Purification
    Purified antibody.
    Immunogen
    BALB/c mice were immunized with human T lymphoblasts and spleen cells of the immunized animals were fused with X63-Ag8.653 mouse myeloma cells. The supernatants of the resultant hybridomas were screened by a proliferation inhibition assay (inhibition of the human T lymphoblast response to IL-2). Two of those (the clones AHT54 and AHT107) that produced antibodies which inhibited IL-2 dependent proliferation of human T lymphoblasts were selected, cloned and recloned.
    Clone
    AHT107
    Isotype
    IgG kappa
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  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Comment

    This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % Proclin 300.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Target
    CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
    Alternative Name
    IL2R (IL2RA Products)
    Synonyms
    CD25 antibody, IDDM10 antibody, IL2R antibody, TCGFR antibody, IL2RAC antibody, IL-2RA antibody, Il2r antibody, Ly-43 antibody, interleukin 2 receptor subunit alpha antibody, interleukin-2 receptor subunit alpha-like antibody, interleukin 2 receptor, alpha chain antibody, IL2RA antibody, Il2ra antibody, LOC100222957 antibody
    Background
    CD25, Interleukin 2 receptor, IL-2R, IL-2 receptor, IL2 receptor, Tac antigen, p55, AHT-107, AHT107
    UniProt
    P01589
    Pathways
    JAK-STAT Signaling, Growth Factor Binding, Activated T Cell Proliferation
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