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HSD3B7 antibody
HSD3B7
Reactivity: Human, Rat
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-HSD3B7 Antibody
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Target
See all HSD3B7 Antibodies
HSD3B7
(Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 7 (HSD3B7))
Reactivity
All reactivities for HSD3B7 antibodies
Human, Rat
Host
All hosts for HSD3B7 antibodies
Rabbit
Clonality
All clonalities for HSD3B7 antibodies
Polyclonal
Conjugate
All conjugates for HSD3B7 antibodies
This HSD3B7 antibody is un-conjugated
Application
All applications for HSD3B7 antibodies
Western Blotting (WB)
Cross-Reactivity
Human, Rat
Purification
Affinity purification
Immunogen
Recombinant protein corresponding to Mouse HSD3B7
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Alternatives
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Application Details
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Application Notes
WB (H,R) 1:500-1:1000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS, pH 7.4, 0.02 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Target Details for HSD3B7
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Target
HSD3B7
(Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 7 (HSD3B7))
Alternative Name
HSD3B7 (HSD3B7 Products )
Synonyms
CBAS1 antibody, PFIC4 antibody, SDR11E3 antibody, AI195443 antibody, BB098564 antibody, Cca2 antibody, hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 antibody, HSD3B7 antibody, Hsd3b7 antibody
Background
This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene.
Molecular Weight
45 kDa
Gene ID
101502
UniProt
Q9EQC1
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