POGLUT1 antibody

Catalog No. ABIN7075265

Product Details anti-POGLUT1 Antibody

Target: POGLUT1 (Protein O-Glucosyltransferase 1 (POGLUT1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POGLUT1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse POGLUT1

Application Details

Application Notes: WB (M) 1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for POGLUT1

Target: POGLUT1 (Protein O-Glucosyltransferase 1 (POGLUT1))

Alternative Name: POGLUT1 (POGLUT1 Products)

Synonyms: C3orf9 antibody, CLP46 antibody, KDELCL1 antibody, KTELC1 antibody, MDSRP antibody, Rumi antibody, hCLP46 antibody, MDS010 antibody, 9630046K23Rik antibody, Ktelc1 antibody, protein O-glucosyltransferase 1 antibody, POGLUT1 antibody, Poglut1 antibody

Background: CLP46 is a KTEL motif-containing protein that belongs to the CAP10 family. The KTEL motif at the C-terminus of CLP46 is an endoplasmic reticulum (ER) retention signal which localizes the CLP46 protein to the lumen of the ER. CLP46 is thought to promote cell proliferation and is also believed to be involved with hepatic functions. The Drosophila protein rumi, a CAP10 protein and likely similar in function to CLP46, uses glucosylation to act as a Notch signaling regulator. Expressed in varying degrees in most adult tissue, CLP46 is especially abundant in the liver. CLP46 is not expressed in detectable levels in colon, thymus or small intestine. Human CLP46 shares 94 % and 91 % sequence similarity with its bovine and mouse homologs, respectively.

Molecular Weight: 40 kDa

Gene ID: 224143

NCBI Accession: NP_759012

UniProt: Q8BYB9

Pathways: Notch Signaling