CD14 antibody (iFluor™647)
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- Target See all CD14 Antibodies
- CD14
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD14 antibody is conjugated to iFluor™647
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Application
- Flow Cytometry (FACS)
- Characteristics
- The clone M5E2, a mouse monoclonal antibody, specifically recognizes a human 53-55 kDa glycosylphosphatidylinositol (GPI)-anchored single chain cell surface antigen known as CD14. The expression of CD14 is commonly observed on monocytes, interfollicular macrophages, reticular dendritic cells and some Langerhans cells. M5E2 binds with a complex of LPS and lipopolysaccharide binding protein, and blockade of CD14 with monoclonal antibodies prevented the synthesis of TNF-alpha by LPS activated leukocytes. M5E2 has crossreactivity with various species including non-human rhesus macaques.
- Purification
- Purified
- Purity
- >95 %
- Grade
- GMP Grade
- Immunogen
- Full-length human CD14 protein
- Clone
- M5E2
- Isotype
- IgG2a kappa
- Top Product
- Discover our top product CD14 Primary Antibody
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anti-CD14 (CD14) (AA 54-83), (N-Term) antibody
CD14 Reactivity: Human FACS, WB, IF, IHC (p) Host: Rabbit Polyclonal RB14105 unconjugated
anti-CD14 (CD14) (AA 20-214) antibodyCD14 Reactivity: Human WB, IHC, ELISA, ICC Host: Mouse Monoclonal 1H5D8 unconjugated
anti-CD14 (CD14) (AA 20-214) antibodyCD14 Reactivity: Human, Mouse FACS, WB, IHC, ELISA Host: Mouse Monoclonal 4B4F12 unconjugated
anti-CD14 (CD14) antibodyCD14 Reactivity: Human IHC, ELISA Host: Mouse Monoclonal 1A3B6 unconjugated
anti-CD14 (CD14) (AA 20-345) antibodyCD14 Reactivity: Human FACS, WB, IHC, ELISA, IF Host: Mouse Monoclonal 14G1F3 unconjugated
anti-CD14 (CD14) (AA 230-345) antibodyCD14 Reactivity: Human FACS, WB, IHC, ELISA Host: Mouse Monoclonal 1D1F8 unconjugated
anti-CD14 (CD14) (AA 25-148) antibodyCD14 Reactivity: Human FACS, WB, IHC, ISt, StM Host: Mouse Monoclonal LPSR-2385 unconjugated
anti-CD14 (CD14) antibodyCD14 Reactivity: Human, Non-Human Primate FACS, WB, ELISA, IP Host: Mouse Monoclonal MEM-18 unconjugated
anti-CD14 (CD14) antibodyCD14 Reactivity: Human, Non-Human Primate FACS, WB, ELISA, IP, Func Host: Mouse Monoclonal MEM-18 unconjugated
anti-CD14 (CD14) (AA 201-300) antibodyCD14 Reactivity: Human, Mouse, Rat, Dog, Sheep, Rabbit WB, ELISA, IHC (p), ICC, IHC (fro), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
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- Target
- CD14
- Alternative Name
- CD14 (CD14 Products)
- Synonyms
- CD14 molecule antibody, CD14 antigen antibody, CD14 antibody, Cd14 antibody
- Background
- Clone M5E2 reacts with a nonfunctional domain of human CD14, a 53-55 kDa glycosylphosphatidylinositol (GPI)- anchored and single chain glycoprotein expressed at high levels on monocytes. Additionally, the CD14 reacts with monocytes, interfollicular macrophages, reticular dendritic cells and some Langerhans cells. The binding of the CD14 does not inhibit CD14 mediated activities, and is useful for detecting CD14 expression by immunofluorescence and or immunocytochemical methods.
- Gene ID
- 929
- UniProt
- P08571
- Pathways
- TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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