LAMP1 antibody
-
- Target See all LAMP1 Antibodies
- LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))
-
Reactivity
- Human
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- This LAMP1 antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Cross-Reactivity
- Human
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human LAMP1
- Clone
- A7D12
- Isotype
- IgG
- Top Product
- Discover our top product LAMP1 Primary Antibody
-
-
- Application Notes
-
WB 1:300-5000
IF()
ICC 1:100-500 - Restrictions
- For Research Use only
-
- Concentration
- 1 mg/mL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
-
- Target
- LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))
- Alternative Name
- LAMP1 (LAMP1 Products)
- Synonyms
- CD107a antibody, LAMPA antibody, LGP120 antibody, AI196048 antibody, Lamp-1 antibody, LEP100 antibody, LAMP-1 antibody, LGP-A antibody, Lgpa antibody, Lysosome-associated membrane protein 1 antibody, cd107a antibody, lamp-1 antibody, lamp1 antibody, lampa antibody, lgp120 antibody, rexp76 antibody, lysosomal associated membrane protein 1 antibody, lysosomal-associated membrane protein 1 antibody, lysosomal-associated membrane protein 1 L homeolog antibody, LAMP1 antibody, Lamp1 antibody, lamp1.L antibody
- Background
-
Synonyms: CD107 antigen like family member A, CD107 antigen-like family member A, CD107a, CD107a antigen, LAMP 1, LAMP-1, LAMP1_HUMAN, LAMPA, LGP120, lgpA, Lysosomal membrane glycoprotein 120KD, Lysosomal Associated Membrane Protein 1, Lysosome associated membrane glycoprotein 1, Lysosome-associated membrane glycoprotein 1, Lysosome-associated membrane glycoprotein 1, Lysosome-associated membrane protein 1, OTTHUMP00000040663.
Background: Lysosome associated membrane protein (LAMP1), also known as lgp120 or lgpA, is a type 1 integral membrane protein that is transported from trans Golgi networks to endosomes and then lysosomes. Upon cell activation, LAMP1 transfer to the plasma membrane is dependent on a carboxyl terminal tyrosine based motif (YXXI). Perturbation in the spacing between the tyrosine based motif relative to the membrane abolishes lysosome localization of LAMP1. This mutant protein then cycles between the plasma membrane and the endosome. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells (PBMC) to vascular endothelium, therefore they are possibly involved in the adhesion of PBMCs to the site of inflammation.
- Gene ID
- 3916
- UniProt
- P11279
- Pathways
- Autophagy
-