CACNA1B antibody

Catalog No. ABIN7112179

Product Details anti-CACNA1B Antibody

Target: CACNA1B (Calcium Channel, Voltage-Dependent, N Type, alpha 1B Subunit (CACNA1B))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CACNA1B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: calcium channel, voltage-dependent, N type, alpha 1B subunit

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:1000, IHC: 1:50-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for CACNA1B

Target: CACNA1B (Calcium Channel, Voltage-Dependent, N Type, alpha 1B Subunit (CACNA1B))

Alternative Name: CACNA1B (CACNA1B Products)

Synonyms: BIII antibody, CACNL1A5 antibody, CACNN antibody, Cav2.2 antibody, AW050276 antibody, AW060892 antibody, AW822256 antibody, Cchn1a antibody, alpha(1B) antibody, calcium voltage-gated channel subunit alpha1 B antibody, calcium channel, voltage-dependent, N type, alpha 1B subunit antibody, CACNA1B antibody, Cacna1b antibody

Background: Synonyms:BIII, Brain calcium channel III, CACH5, CACNA1B, CACNL1A5, CACNN, Cav2.2 Background:Voltage-sensitive calcium channels(VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated'(HVA) group and are blocked by omega-conotoxin-GVIA(omega-CTx-GVIA) and by omega-agatoxin-IIIA(omega-Aga-IIIA). They are however insensitive to dihydropyridines(DHP), and omega-agatoxin-IVA(omega-Aga-IVA). Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons.

Molecular Weight: 262 kDa

Gene ID: 774

UniProt: Q00975