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FRS2 antibody
FRS2
Reactivity: Human, Mouse, Rat
WB, ELISA, IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-FRS2 Antibody
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Target
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FRS2
(Fibroblast Growth Factor Receptor Substrate 2 (FRS2))
Reactivity
All reactivities for FRS2 antibodies
Human, Mouse, Rat
Host
All hosts for FRS2 antibodies
Rabbit
Clonality
All clonalities for FRS2 antibodies
Polyclonal
Conjugate
All conjugates for FRS2 antibodies
This FRS2 antibody is un-conjugated
Application
All applications for FRS2 antibodies
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
Purification
Immunogen affinity purified
Purity
≥95 % as determined by SDS-PAGE
Immunogen
fibroblast growth factor receptor substrate 2
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
WB: 1:500-1:5000, IHC: 1:20-1:200, IF: 1:10-1:100
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Expiry Date
12 months
Target Details for FRS2
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Target
FRS2
(Fibroblast Growth Factor Receptor Substrate 2 (FRS2))
Alternative Name
FRS2 (FRS2 Products )
Synonyms
frs2 antibody, wu:fd21h10 antibody, zgc:91973 antibody, FRS2A antibody, FRS2alpha antibody, SNT antibody, SNT-1 antibody, SNT1 antibody, 4732458E18 antibody, C330018A15Rik antibody, Frs2alpha antibody, fibroblast growth factor receptor substrate 2 antibody, fibroblast growth factor receptor substrate 2b antibody, FRS2 antibody, frs2b antibody, Frs2 antibody
Background
Synonyms:FGFR signaling adaptor SNT, FGFR substrate 2, FRS2, FRS2A, FRS2alpha, SNT, SNT 1, SNT1 Background:Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.
Molecular Weight
60 kDa
Gene ID
10818
UniProt
Q8WU20
Pathways
Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Signaling Events mediated by VEGFR1 and VEGFR2
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