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HSD3B7 antibody
HSD3B7
Reactivity: Human, Mouse
ELISA, WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-HSD3B7 Antibody
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Target
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HSD3B7
(Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 7 (HSD3B7))
Reactivity
All reactivities for HSD3B7 antibodies
Human, Mouse
Host
All hosts for HSD3B7 antibodies
Rabbit
Clonality
All clonalities for HSD3B7 antibodies
Polyclonal
Conjugate
All conjugates for HSD3B7 antibodies
This HSD3B7 antibody is un-conjugated
Application
All applications for HSD3B7 antibodies
ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
Purification
Immunogen affinity purified
Purity
≥95 % as determined by SDS-PAGE
Immunogen
hydroxy-delta-5-steroid dehydrogenase, 3 beta-and steroid delta-isomerase 7
Isotype
IgG
Top Product
Discover our top product HSD3B7 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB: 1:500-1:2000, IHC: 1:20-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Expiry Date
12 months
Target Details for HSD3B7
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Target
HSD3B7
(Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 7 (HSD3B7))
Alternative Name
HSD3B7 (HSD3B7 Products )
Synonyms
CBAS1 antibody, PFIC4 antibody, SDR11E3 antibody, AI195443 antibody, BB098564 antibody, Cca2 antibody, hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 antibody, HSD3B7 antibody, Hsd3b7 antibody
Background
Synonyms: Background:The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. HSD VII is active against four 7-alpha-hydroxylated sterols. Does not metabolize several different C(19/21) steroids as substrates. Involved in bile acid synthesis(PubMed:11067870). Plays a key role in cell positioning and movement in lymphoid tissues by mediating degradation of 7-alpha,25-dihydroxycholesterol(7-alpha,25-OHC): 7-alpha,25-OHC acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells.
Molecular Weight
36 kDa
Gene ID
80270
UniProt
Q9H2F3
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