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NFE2 antibody
NFE2
Reactivity: Human
WB, ELISA, IHC, IF, IP
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-NFE2 Antibody
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Target
See all NFE2 Antibodies
NFE2
(Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2))
Reactivity
All reactivities for NFE2 antibodies
Human
Host
All hosts for NFE2 antibodies
Rabbit
Clonality
All clonalities for NFE2 antibodies
Polyclonal
Conjugate
All conjugates for NFE2 antibodies
This NFE2 antibody is un-conjugated
Application
All applications for NFE2 antibodies
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
Purification
Immunogen affinity purified
Purity
≥95 % as determined by SDS-PAGE
Immunogen
nuclear factor(erythroid-derived 2), 45kDa
Isotype
IgG
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Discover our top product NFE2 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Expiry Date
12 months
Target Details for NFE2
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Target
NFE2
(Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2))
Alternative Name
NFE2 (NFE2 Products )
Synonyms
NF-E2 antibody, p45 antibody, 45kDa antibody, p45NFE2 antibody, p45nf-e2 antibody, nuclear factor, erythroid 2 antibody, nuclear factor, erythroid derived 2 antibody, NFE2 antibody, Nfe2 antibody
Background
Synonyms: Background:Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2(HS2) of the beta-globin control region(LCR). This subunit(NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.
Molecular Weight
45 kDa
Gene ID
4778
UniProt
Q16621
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