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Endoglin antibody (AA 58-110) (HRP)

ENG Reactivity: Human, Mouse, Rat, Dog WB, ELISA, IHC (fro), IHC (p) Host: Rabbit Polyclonal HRP
Catalog No. ABIN707570
  • Target See all Endoglin (ENG) Antibodies
    Endoglin (ENG)
    Binding Specificity
    • 15
    • 14
    • 12
    • 12
    • 7
    • 7
    • 7
    • 7
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 58-110
    Reactivity
    • 164
    • 61
    • 43
    • 16
    • 10
    • 3
    • 2
    • 1
    Human, Mouse, Rat, Dog
    Host
    • 106
    • 80
    • 16
    • 1
    • 1
    Rabbit
    Clonality
    • 106
    • 97
    • 1
    Polyclonal
    Conjugate
    • 89
    • 27
    • 25
    • 24
    • 15
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Endoglin antibody is conjugated to HRP
    Application
    • 145
    • 120
    • 58
    • 56
    • 32
    • 17
    • 15
    • 14
    • 13
    • 13
    • 13
    • 7
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Dog, Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CD105
    Isotype
    IgG
    Top Product
    Discover our top product ENG Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handling Advice
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    Endoglin (ENG)
    Alternative Name
    CD105 (ENG Products)
    Synonyms
    ENG antibody, MGC137842 antibody, DKFZp469D0419 antibody, END antibody, HHT1 antibody, ORW1 antibody, AI528660 antibody, AI662476 antibody, CD105 antibody, S-endoglin antibody, endoglin antibody, ENG antibody, Eng antibody
    Background

    Synonyms: END, HHT1, ORW1, Endoglin, CD15, ENG

    Background: Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGF-beta1 signaling through SMAD3.

    Gene ID
    2022
    UniProt
    P17813
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