×
For best experience we recommend to activate Javascript in your browser.
SNCA antibody
SNCA
Reactivity: Human, Rat, Mouse
WB, ELISA, IHC
Host: Mouse
Monoclonal
5C6
unconjugated
Product Details anti-SNCA Antibody
(hide)
Target
See all SNCA Antibodies
SNCA
(Synuclein, alpha (SNCA))
Reactivity
All reactivities for SNCA antibodies
Human, Rat, Mouse
Host
All hosts for SNCA antibodies
Mouse
Clonality
All clonalities for SNCA antibodies
Monoclonal
Conjugate
All conjugates for SNCA antibodies
This SNCA antibody is un-conjugated
Application
All applications for SNCA antibodies
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
Purification
protein A+G purified
Purity
≥95 % as determined by SDS-PAGE
Immunogen
synuclein, alpha (non A4 component of amyloid precursor)
Clone
5C6
Isotype
IgG1
Top Product
Discover our top product SNCA Primary Antibody
Alternatives
(show)
Application Details
(hide)
Application Notes
WB: 1:500 - 1:2000, IHC: 1:500 - 1:2000
Restrictions
For Research Use only
Handling
(hide)
Format
Liquid
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Expiry Date
12 months
Target Details for SNCA
(hide)
Target
SNCA
(Synuclein, alpha (SNCA))
Alternative Name
alpha-synuclein (SNCA Products )
Synonyms
snca antibody, MGC64356 antibody, LOC619283 antibody, NACP antibody, alphaSYN antibody, PARK1 antibody, PARK4 antibody, PD1 antibody, synuclein alpha L homeolog antibody, alpha-synuclein antibody, synuclein alpha antibody, synuclein, alpha antibody, snca.L antibody, LOC619283 antibody, SNCA antibody, Snca antibody
Background
Synonyms:Alpha synuclein, NACP, PARK1, PARK4, SNCA Background:Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.
Molecular Weight
18 kDa
Gene ID
6622
UniProt
P37840
Pathways
Synaptic Membrane , Regulation of G-Protein Coupled Receptor Protein Signaling , Positive Regulation of Endopeptidase Activity , Regulation of Carbohydrate Metabolic Process , Platelet-derived growth Factor Receptor Signaling , Negative Regulation of Transporter Activity , Regulation of long-term Neuronal Synaptic Plasticity
Recently viewed
(hide)