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ANTXR1 antibody

ANTXR1 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7128422
  • Target See all ANTXR1 Antibodies
    ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
    Reactivity
    • 75
    • 35
    • 19
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 69
    • 3
    • 3
    Rabbit
    Clonality
    • 72
    • 3
    Polyclonal
    Conjugate
    • 29
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ANTXR1 antibody is un-conjugated
    Application
    • 43
    • 29
    • 14
    • 13
    • 13
    • 12
    • 7
    • 5
    • 3
    • 3
    • 3
    Western Blotting (WB), ELISA
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Antigen affinity purification
    Immunogen
    Fusion protein of Human ANTXR1
    Isotype
    IgG
    Top Product
    Discover our top product ANTXR1 Primary Antibody
  • Application Notes
    ELISA:1:1000-1:2000, WB:1:200-1:1000,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
    Alternative Name
    ANTXR1 (ANTXR1 Products)
    Synonyms
    ANTXR1 antibody, ATR antibody, TEM8 antibody, 2310008J16Rik antibody, 2810405N18Rik antibody, Antrx1 antibody, Tem8 antibody, anthrax toxin receptor 1 antibody, ANTXR1 antibody, Antxr1 antibody
    Background

    Background: This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.

    Aliases: Anthrax toxin receptor 1 antibody, ANTR1_HUMAN antibody, Antxr1 antibody, ATR antibody, Tumor endothelial marker 8 antibody

    UniProt
    Q9H6X2
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