Dynamin 1-Like antibody (pSer637)

Catalog No. ABIN7138759

Product Details anti-Dynamin 1-Like Antibody

Target: Dynamin 1-Like (DNM1L)

Binding Specificity: pSer637

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dynamin 1-Like antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human, Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of Serine637(K-L-S(p)-A-R) derived from Human DRP1.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:1000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Dynamin 1-Like

Target: Dynamin 1-Like (DNM1L)

Alternative Name: DNM1L (DNM1L Products)

Synonyms: DLP1 antibody, DRP1 antibody, DVLP antibody, DYMPLE antibody, EMPF antibody, HDYNIV antibody, 6330417M19Rik antibody, AI450666 antibody, Dlp1 antibody, Dnmlp1 antibody, Drp1 antibody, python antibody, Dnml1 antibody, dnm1l antibody, MGC53850 antibody, zgc:66163 antibody, DNM1L antibody, 18.m06247 antibody, CG3210 antibody, DRP antibody, Dmel\CG3210 antibody, Dnm1/Drp1 antibody, Drp antibody, Drp-1 antibody, drp-1 antibody, drp1 antibody, frat antibody, l(2)22Fc antibody, l(2)22Fd antibody, l(2)ND2 antibody, l(2)ND3 antibody, dynamin 1 like antibody, dynamin 1-like antibody, dynamin 1-like L homeolog antibody, dynamin-1-like antibody, dynamin-1-like protein antibody, dynamin-like protein antibody, Dynamin related protein 1 antibody, DNM1L antibody, Dnm1l antibody, dnm1l.L antibody, dnm1l antibody, LOC100369408 antibody, LOC411472 antibody, dyn1 antibody, cgd1_580 antibody, EHI_052740 antibody, PVX_092875 antibody, BBOV_II002980 antibody, Drp1 antibody

Background:

Background:

Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Through its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. Facilitates developmentally regulated apoptosis during neural tube formation.

Shin H.-W., J. Biochem. 122:525-530(1997).
Hong Y.-R., Biochem. Biophys. Res. Commun. 249:697-703(1998).
Imoto M., J. Cell Sci. 111:1341-1349(1998).

Aliases: DLP1 antibody, dnm1l antibody, DNM1L_HUMAN antibody, Dnm1p/Vps1p-like protein antibody, dnml1 antibody, DRP1 antibody, DVLP antibody, Dymple antibody, Dynamin 1 like antibody, Dynamin family member proline-rich carboxyl-terminal domain less antibody, Dynamin like protein antibody, Dynamin related protein 1 antibody, Dynamin-1-like protein antibody, Dynamin-like protein 4 antibody, Dynamin-like protein antibody, Dynamin-like protein IV antibody, Dynamin-related protein 1 antibody, DYNIV 11 antibody, EMPF antibody, EMPF1 antibody, FLJ41912 antibody, HdynIV antibody, VPS1 antibody

UniProt: O00429