TLR2 antibody (AA 19-588) (FITC)

Catalog No. ABIN7349153

Product Details anti-TLR2 Antibody (FITC)

Target: TLR2 (Toll-Like Receptor 2 (TLR2))

Binding Specificity: AA 19-588

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLR2 antibody is conjugated to FITC

Application: Please inquire

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Toll-like receptor 2 protein (19-588AA)

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TLR2

Target: TLR2 (Toll-Like Receptor 2 (TLR2))

Alternative Name: TLR2 (TLR2 Products)

Synonyms: CD282 antibody, TIL4 antibody, Ly105 antibody, toll like receptor 2 antibody, toll-like receptor 2 antibody, TLR2 antibody, Tlr2 antibody, tlr2 antibody

Background:

Background: Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6.

Aliases: CD282 antibody, CD282 antigen antibody, TIL 4 antibody, TIL4 antibody, TLR 2 antibody, TLR2 antibody, TLR2_HUMAN antibody, Toll like receptor 2 antibody, Toll like receptor 2 precursor antibody, Toll-like receptor 2 antibody, Toll/interleukin 1 receptor like 4 antibody, Toll/interleukin 1 receptor like protein 4 antibody, Toll/interleukin receptor like protein 4 antibody, Toll/interleukin-1 receptor-like protein 4 antibody

UniProt: O60603

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades