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CD14 antibody (Biotin)

CD14 Reactivity: Human FACS, IF, ELISA Host: Mouse Monoclonal Biotin
Catalog No. ABIN7178397
  • Target See all CD14 Antibodies
    CD14
    Reactivity
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    • 45
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    Human
    Host
    • 185
    • 58
    • 16
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    Mouse
    Clonality
    • 203
    • 60
    Monoclonal
    Conjugate
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    This CD14 antibody is conjugated to Biotin
    Application
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    Flow Cytometry (FACS), Immunofluorescence (IF), ELISA
    Cross-Reactivity
    Human
    Purification
    Affinity purified
    Immunogen
    Recombinant Protein
    Isotype
    IgG1, IgG1 kappa
    Top Product
    Discover our top product CD14 Primary Antibody
  • Application Notes
    Recommended dilution:IF:1:100-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Phosphate-buffered solution, pH 7.4, containing 0.09 % sodium azide and 0.2 % (w/v) BSA
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    CD14
    Alternative Name
    CD14 (CD14 Products)
    Synonyms
    CD14 molecule antibody, CD14 antigen antibody, CD14 antibody, Cd14 antibody
    Background

    Background: 4AW4 reacts with CD14, a 53-55 kDa molecule. CD14 is a human high affinity cell-surface receptor for complexes of lipopolysaccharide (LPS-endotoxin) and serum LPS-binding protein (LPB). CD14 antigen has a strong presence on the surface of monocytes/macrophages, is weakly expressed on granulocytes, but not expressed by myeloid progenitor cells. CD14 functions as a receptor for endotoxin; when the monocytes become activated they release cytokines such as TNF, and up-regulate cell surface molecules including adhesion molecules.This clone is cross reactive with non-human primate.1.  Knapp, W et al., eds. (1989) Leucocyte Typing IV : White Cell Differentiation Antigens, Oxford University Press, New York.2.  Makgoba, MW et al., (1988) Nature 331: 86-883.  Boyd. AW et al. (1989) Blood  73: 1896-1903

    Aliases: N/A

    UniProt
    P08571
    Pathways
    TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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