IL1R2 antibody (AA 14-343)
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- Target See all IL1R2 Antibodies
- IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))
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Binding Specificity
- AA 14-343
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This IL1R2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- Purification
- purified
- Immunogen
- Purified recombinant fragment of human CD121B (AA: extra 14-343) expressed in HEK293-6e cells supernatant.
- Clone
- 3G1D8
- Isotype
- IgG1
- Top Product
- Discover our top product IL1R2 Primary Antibody
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- Application Notes
- WB:1:500 - 1:2000, FCM:1:200 - 1:400, ELISA:1:10000,
- Restrictions
- For Research Use only
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- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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- Target
- IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))
- Alternative Name
- CD121B (IL1R2 Products)
- Synonyms
- CD121b antibody, CDw121b antibody, IL-1R-2 antibody, IL-1RT-2 antibody, IL-1RT2 antibody, IL1R2c antibody, IL1RB antibody, Il1r-2 antibody, IL-1R2 antibody, interleukin 1 receptor type 2 antibody, interleukin 1 receptor, type II antibody, interleukin-like antibody, IL1R2 antibody, Il1r2 antibody, KK34 antibody
- Background
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Description: The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage.
Aliases: IL1R2,IL1RB, IL1R2c, CDw121b, IL-1R-2, IL-1RT2, IL-1RT-2
- Molecular Weight
- 45.4 kDa
- Gene ID
- 7850
- Pathways
- NF-kappaB Signaling
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