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TIMD4 antibody (AA 75-170)

TIMD4 Reactivity: Human WB, ELISA, IHC (p), IHC (fro), IF (p), IF (cc) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN715631
  • Target See all TIMD4 Antibodies
    TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))
    Binding Specificity
    • 13
    • 9
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 75-170
    Reactivity
    • 34
    • 17
    • 5
    • 2
    • 1
    Human
    Host
    • 31
    • 6
    • 3
    • 2
    • 1
    Rabbit
    Clonality
    • 30
    • 12
    • 1
    Polyclonal
    Conjugate
    • 27
    • 4
    • 3
    • 3
    • 3
    • 3
    This TIMD4 antibody is un-conjugated
    Application
    • 30
    • 25
    • 12
    • 10
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Predicted Reactivity
    Human,Mouse,Rat,Cow,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human TIM4
    Isotype
    IgG
    Top Product
    Discover our top product TIMD4 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))
    Alternative Name
    Tim4 (TIMD4 Products)
    Synonyms
    RGD1564516 antibody, MGC99322 antibody, TIMD4 antibody, B430010N18Rik antibody, TIM-4 antibody, Tim4 antibody, SMUCKLER antibody, TIM4 antibody, T-cell immunoglobulin and mucin domain containing 4 antibody, T-cell immunoglobulin and mucin domain containing 4 L homeolog antibody, T cell immunoglobulin and mucin domain containing 4 antibody, Timd4 antibody, TIMD4 antibody, timd4.L antibody
    Background

    Synonyms: SMUCKLER, Spleen, mucin-containing, knockout of lymphotoxin protein, T cell immunoglobulin and mucin domain containing protein 4, T-cell immunoglobulin and mucin domain containing 4, T-cell membrane protein 4, TIM-4, Tim4, Tim 4, TIMD 4.

    Background: The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors that are involved in the regulation of T helper (Th) -1 and -2 cell-mediated immunity. Studies have shown that TIM 4, which is preferentially expressed on macrophages and dendritic cells, is the natural ligand of TIM 1, and that this binding leads to T-cell expansion and cytokine production. Unlike other members of the TIM family, TIM 4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain. The TIM 4 gene maps to a locus associated with predisposition to asthma in both mice and humans and with its connection to TIM 1-triggered Th2 responsiveness, may be considered as a candidate disease/predisposition gene for asthma.

    Gene ID
    91937
    Pathways
    Cancer Immune Checkpoints
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