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IGF1R antibody (pTyr1131, pTyr1146)
IGF1R
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-IGF1R Antibody
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Target
See all IGF1R Antibodies
IGF1R
(Insulin-Like Growth Factor 1 Receptor (IGF1R))
Binding Specificity
All epitopes for IGF1R antibodies
pTyr1131, pTyr1146
Reactivity
All reactivities for IGF1R antibodies
Human
Host
All hosts for IGF1R antibodies
Rabbit
Clonality
All clonalities for IGF1R antibodies
Polyclonal
Conjugate
All conjugates for IGF1R antibodies
This IGF1R antibody is un-conjugated
Application
All applications for IGF1R antibodies
Western Blotting (WB)
Purpose
Phospho-INSR-Y1146/IGF1R-Y1131 Rabbit pAb
Cross-Reactivity
Human
Characteristics
Phosphorylated Antibodies
Purification
Affinity purification
Immunogen
A synthetic phosphorylated peptide around Y1146 of human INSR and Y1131 of human IGF1R.
Isotype
IgG
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Discover our top product IGF1R Primary Antibody
Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for IGF1R
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Target
IGF1R
(Insulin-Like Growth Factor 1 Receptor (IGF1R))
Alternative Name
IGF1R/INSR (IGF1R Products )
Synonyms
CMT2N antibody, CD221 antibody, IGFIR antibody, IGFR antibody, JTK13 antibody, IGFIRC antibody, IGFR1 antibody, IGF-1R antibody, IGF1R antibody, DKFZp469I0618 antibody, igf-1r antibody, xIGF-1R antibody, xIGFR antibody, xigf1r antibody, A330103N21Rik antibody, D930020L01 antibody, hyft antibody, igf-ir antibody, IGF-IR antibody, IGF-IRb antibody, wu:fb03h06 antibody, IGF-IRa antibody, sb:eu1090 antibody, wu:fi20b10 antibody, alanyl-tRNA synthetase antibody, insulin like growth factor 1 receptor antibody, insulin-like growth factor 1 receptor antibody, insulin-like growth factor 1 antibody, insulin-like growth factor I receptor antibody, insulin like growth factor 1 receptor S homeolog antibody, insulin-like growth factor 1b receptor antibody, insulin-like growth factor 1a receptor antibody, AARS antibody, IGF1R antibody, Igf1r antibody, igf1r antibody, Igf1 antibody, LOC780503 antibody, LOC100136427 antibody, igf1r.S antibody, igf1rb antibody, igf1ra antibody
Background
This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],INSR/IGF1R,Protein phosphorylation,Protein phosphorylation,Protein phosphorylation,IGF1R/INSR
Molecular Weight
155kDa
Gene ID
3643, 3480
UniProt
P06213 , P08069
Pathways
RTK Signaling , Regulation of Hormone Metabolic Process , Regulation of Hormone Biosynthetic Process , Autophagy
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