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JAK1 antibody (AA 120-380)
JAK1
Reactivity: Human
WB, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-JAK1 Antibody
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Target
See all JAK1 Antibodies
JAK1
(Janus Kinase 1 (JAK1))
Binding Specificity
All epitopes for JAK1 antibodies
AA 120-380
Reactivity
All reactivities for JAK1 antibodies
Human
Host
All hosts for JAK1 antibodies
Rabbit
Clonality
All clonalities for JAK1 antibodies
Polyclonal
Conjugate
All conjugates for JAK1 antibodies
This JAK1 antibody is un-conjugated
Application
All applications for JAK1 antibodies
Western Blotting (WB), Immunofluorescence (IF)
Purpose
JAK1 Rabbit pAb
Sequence
NDNEQSVWRH SPKKQKNGYE KKKIPDATPL LDASSLEYLF AQGQYDLVKC LAPIRDPKTE QDGHDIENEC LGMAVLAISH YAMMKKMQLP ELPKDISYKR YIPETLNKSI RQRNLLTRMR INNVFKDFLK EFNNKTICDS SVSTHDLKVK YLATLETLTK HYGAEIFETS MLLISSENEM NWFHSNDGGN VLYYEVMVTG NLGIQWRHKP NVVSVEKEKN KLKRKKLENK HKKDEEKNKI REEWNNFSYF PEITHIVIKE S
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Polyclonal Antibodies
Purification
Affinity purification
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 120-380 of human JAK1 (NP_002218.2).
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:1000,IF,1:50 - 1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for JAK1
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Target
JAK1
(Janus Kinase 1 (JAK1))
Alternative Name
JAK1 (JAK1 Products )
Synonyms
JAK1A antibody, JAK1B antibody, JTK3 antibody, AA960307 antibody, C130039L05Rik antibody, wu:fb93e10 antibody, jak1 antibody, Janus kinase 1 antibody, tyrosine-protein kinase JAK1 antibody, JAK1 antibody, Jak1 antibody, jak1 antibody, LOC100286690 antibody
Background
This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants.,JAK1,JAK1A,JAK1B,JTK3,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Kinase,Tyrosine kinases,PI3K-Akt Signaling Pathway,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Inhibition of Apoptosis,Immunology & Inflammation,Cytokines,IL-6 Receptor Signaling Pathway,JAK1
Molecular Weight
133kDa
Gene ID
3716
UniProt
P23458
Pathways
JAK-STAT Signaling , RTK Signaling , Interferon-gamma Pathway , Hepatitis C , Toll-Like Receptors Cascades , Unfolded Protein Response
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