MTOR antibody (pSer2481)

Catalog No. ABIN7268436

Product Details anti-MTOR Antibody

Target: MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))

Binding Specificity: pSer2481

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MTOR antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Phospho-mTOR-S2481 Rabbit mAb

Cross-Reactivity: Human, Mouse

Characteristics: Phosphorylated Antibodies

Purification: Affinity purification

Immunogen: A phospho specific peptide corresponding to residues surrounding S2481 of human mTOR

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MTOR

Target: MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))

Alternative Name: MTOR (mTOR Products)

Synonyms: FRAP1 antibody, FRAP antibody, FRAP2 antibody, RAFT1 antibody, RAPT1 antibody, 2610315D21Rik antibody, AI327068 antibody, Frap1 antibody, flat antibody, frap1 antibody, tor antibody, wu:fc22h08 antibody, mechanistic target of rapamycin kinase antibody, mechanistic target of rapamycin antibody, mechanistic target of rapamycin (serine/threonine kinase) antibody, MTOR antibody, Mtor antibody, mtor antibody

Background: The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Sep 2008],FRAP, FRAP1, FRAP2, RAFT1, RAPT1, SKS,AMPK Signaling Pathway,Angiogenesis,Autophagy,Autophagy_Regulator,B Cell Receptor Signaling Pathway,Cancer,Cardiovascular,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Cell cycle inhibitors,DNA Damage & Repair,Endocrine & Metabolism,Endocrine and metabolic diseases,Endocrine and metabolic diseases_Obesity,Epigenetics & Nuclear Signaling,ErbB-HER Signaling Pathway,Heart,Heart_Cardiogenesis,IL-6 Receptor Signaling Pathway,Immunology & Inflammation,Insulin Receptor Signaling Pathway,Kinase,Kinase_Serine/threonine kinases,mTOR Signaling Pathway,PI3K-Akt Signaling Pathway,Protein phosphorylation,Signal Transduction,T Cell Receptor Signaling Pathway,TGF-b-Smad Signaling Pathway,Transcription Factors,Translation Control,Translational Control_Regulation of eIF4 and p70 S6 Kinase,Warburg Effect,MTOR

Molecular Weight: 289kDa

Gene ID: 2475

UniProt: P42345

Pathways: PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, BCR Signaling, Warburg Effect