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PAK2 antibody (AA 1-212)
KO Validated
PAK2
Reactivity: Human
WB, IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PAK2 Antibody
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Target
See all PAK2 Antibodies
PAK2
(P21-Activated Kinase 2 (PAK2))
Binding Specificity
All epitopes for PAK2 antibodies
AA 1-212
Reactivity
All reactivities for PAK2 antibodies
Human
Host
All hosts for PAK2 antibodies
Rabbit
Clonality
All clonalities for PAK2 antibodies
Polyclonal
Conjugate
All conjugates for PAK2 antibodies
This PAK2 antibody is un-conjugated
Application
All applications for PAK2 antibodies
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Purpose
[KO Validated] PAK2 Rabbit pAb
Sequence
MSDNGELEDK PPAPPVRMSS TIFSTGGKDP LSANHSLKPL PSVPEEKKPR HKIISIFSGT EKGSKKKEKE RPEISPPSDF EHTIHVGFDA VTGEFTGMPE QWARLLQTSN ITKLEQKKNP QAVLDVLKFY DSNTVKQKYL SFTPPEKDGF PSGTPALNAK GTEAPAVVTE EEDDDEETAP PVIAPRPDHT KSIYTRSVID PVPAPVGDSH VD
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Polyclonal Antibodies
Purification
Affinity purification
Grade
KO Validated
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-212 of human PAK2 (NP_002568.2).
Isotype
IgG
Top Product
Discover our top product PAK2 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for PAK2
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Target
PAK2
(P21-Activated Kinase 2 (PAK2))
Alternative Name
PAK2 (PAK2 Products )
Synonyms
PAK65 antibody, PAKgamma antibody, gamma-PAK antibody, 5330420P17Rik antibody, A130002K10Rik antibody, AI836325 antibody, D16Ertd269e antibody, PAK-2 antibody, mKIAA4182 antibody, pak2 antibody, cb422 antibody, kinase antibody, zgc:91798 antibody, wu:fb71h01 antibody, si:dz198m22.1 antibody, pak65 antibody, pakgamma antibody, PAKI antibody, Pak3 antibody, CH73-159L23.1 antibody, wu:fc52b03 antibody, zgc:113857 antibody, p21 (RAC1) activated kinase 2 antibody, p21 protein (Cdc42/Rac)-activated kinase 2 antibody, p21 protein (Cdc42/Rac)-activated kinase 2a antibody, p21 protein (Cdc42/Rac)-activated kinase 2 S homeolog antibody, p21 protein (Cdc42/Rac)-activated kinase 2b antibody, PAK2 antibody, Pak2 antibody, pak2a antibody, pak2.S antibody, pak2b antibody
Background
The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.,PAK2,PAK65,PAKgamma,Cancer,Signal Transduction,Kinase,Serine/threonine kinases,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Microtubules,TGF-b-Smad Signaling Pathway,Immunology & Inflammation,PAK2
Molecular Weight
58kDa
Gene ID
5062
UniProt
Q13177
Pathways
MAPK Signaling , RTK Signaling , TCR Signaling , Fc-epsilon Receptor Signaling Pathway , Regulation of Lipid Metabolism by PPARalpha
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