RC3H1 antibody (AA 834-1133)

Catalog No. ABIN7270049

Product Details anti-RC3H1 Antibody

Target: RC3H1 (Ring Finger and CCCH-Type Domains 1 (RC3H1))

Binding Specificity: AA 834-1133

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RC3H1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: RC3H1 Rabbit pAb

Sequence: AAGSVEMMNV ESKGMRDQRL DLQRRAAETS DDDLIPFGDR PTVSRFGAIS RTSKTIYQGA GPMQAMAPQG APTKSINISD YSPYGTHGGW GASPYSPHQN IPSQGHFSER ERISMSEVAS HGKPLPSAER EQLRLELQQL NHQISQQTQL RGLEAVSNRL VLQREANTLA GQSQPPPPPP PKWPGMISSE QLSLELHQVE REIGKRTREL SMENQCSLDM KSKLNTSKQA ENGQPEPQNK VPAEDLTLTF SDVPNGSALT QENISLLSNK TSSLNLSEDP EGGGDNNDSQ RSGVTPSSAP

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 834-1133 of human RC3H1 (NP_742068.1).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RC3H1

Target: RC3H1 (Ring Finger and CCCH-Type Domains 1 (RC3H1))

Alternative Name: RC3H1 (RC3H1 Products)

Background: This gene encodes a protein containing RING-type and C3H1-type zinc finger motifs. The encoded protein recognizes and binds to a constitutive decay element (CDE) in the 3' UTR of mRNAs, leading to mRNA deadenylation and degradation. Alternative splicing results in multiple transcript variants.,RC3H1,RNF198,ROQUIN,roquin-1,Epigenetics & Nuclear Signaling,RNA Binding,Cell Biology & Developmental Biology,Cell Cycle,Ubiquitin,RC3H1

Molecular Weight: 124kDa/125kDa

Gene ID: 149041

UniProt: Q5TC82

Pathways: Ribonucleoprotein Complex Subunit Organization, Activated T Cell Proliferation