RC3H1 antibody (AA 500-550)
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- Target See all RC3H1 Antibodies
- RC3H1 (Ring Finger and CCCH-Type Domains 1 (RC3H1))
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Binding Specificity
- AA 500-550
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RC3H1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunoprecipitation (IP)
- Purpose
- Rabbit anti-Roquin Antibody, Affinity Purified
- Purification
- Affinity Purified
- Immunogen
- between AA 500 and 550
- Isotype
- IgG
- Top Product
- Discover our top product RC3H1 Primary Antibody
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- Application Notes
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IP: 2 - 5 μg/mg lysate
WB: 1:500 - 1:5,000
- Restrictions
- For Research Use only
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- Concentration
- 1000 μg/mL
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Expiry Date
- 12 months
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- Target
- RC3H1 (Ring Finger and CCCH-Type Domains 1 (RC3H1))
- Alternative Name
- Roquin (RC3H1 Products)
- Synonyms
- RNF198 antibody, ROQUIN antibody, RC3H1 antibody, si:dkey-192m14.4 antibody, 5730557L09Rik antibody, Gm551 antibody, N28103 antibody, mKIAA2025 antibody, RGD1563512 antibody, rc3h1 antibody, ring finger and CCCH-type domains 1 antibody, ring finger and CCCH-type domains 1a antibody, ring finger and CCCH-type zinc finger domains 1 antibody, RING CCCH (C3H) domains 1 antibody, ring finger and CCCH-type domains 1 L homeolog antibody, RC3H1 antibody, rc3h1a antibody, Rc3h1 antibody, rc3h1.L antibody
- Background
- Background: The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Targeting of proteins by ubiquitination occurs in three main steps that involve the activation of ubiquitin by E1 enzymes, the carrying of ubiquitin to the target protein by E2 enzymes and the ligation of ubiquitin to the target protein by E3 enzymes. Roquin is a member of the RING type E3 ubiquitin ligases. Roquin possesses a CCCH zinc-finger found in RNA-binding proteins and is implicated to play a role in the development of autoimmune disease.
- Gene ID
- 149041
- NCBI Accession
- NP_742068
- UniProt
- Q5TC82
- Pathways
- Ribonucleoprotein Complex Subunit Organization, Activated T Cell Proliferation
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