JNK antibody
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- Target See all JNK (MAPK8) Antibodies
- JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))
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Reactivity
- Mouse, Rat
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This JNK antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Purification
- Affinity Purified
- Clone
- R08-6G2
- Isotype
- IgG
- Top Product
- Discover our top product MAPK8 Primary Antibody
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- Application Notes
- WB 1:500-1:1000 IF 1:50-1:100
- Restrictions
- For Research Use only
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- Concentration
- 300 μg/mL
- Buffer
- 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))
- Alternative Name
- JNK (MAPK8 Products)
- Synonyms
- JNK antibody, JNK-46 antibody, JNK1 antibody, JNK1A2 antibody, JNK21B1/2 antibody, PRKM8 antibody, SAPK1 antibody, SAPK1c antibody, AI849689 antibody, Prkm8 antibody, BSK antibody, BSK/DJNK antibody, Bsk antibody, CG5680 antibody, D-JNK antibody, D-junk antibody, DBSK/JNK antibody, DJNK antibody, DJNK/bsk antibody, Dmel\\CG5680 antibody, JNK/SAPK antibody, Jnk antibody, Junk antibody, SAPKa antibody, c-Jun antibody, dJNK antibody, jnk antibody, T10F20.15 antibody, jnk1 antibody, sapk1 antibody, mapk8 antibody, zgc:112379 antibody, JNKb antibody, mapk8b antibody, mitogen-activated protein kinase 8 antibody, Stress-activated protein kinase jnk-1 antibody, basket antibody, Protein kinase superfamily protein antibody, mitogen-activated protein kinase 8 L homeolog antibody, mitogen-activated protein kinase 8b antibody, mitogen-activated protein kinase 8B-like antibody, MAPK8 antibody, jnk-1 antibody, Mapk8 antibody, bsk antibody, ATMPK8 antibody, mapk8.L antibody, mapk8b antibody, LOC109094263 antibody
- Background
- AI849689,c Jun N terminal kinase 1,C-JUN kinase 1,c-Jun N-terminal kinase 1,EC 2.7.11.24,JNK 1,JNK,JNK-46,JNK1A2,JNK21B1/2,MAP kinase 8,MAPK 8,mapk8,Mitogen activated protein kinase 8,Mitogen-activated protein kinase 8,MK08,p54 gamma,Prkm8,Protein kinase JNK1,Protein kinase,mitogen-activated,8,SAPK 1,SAPK gamma,SAPK1,Stress-activated protein kinase 1,Stress-activated protein kinase JNK1,MAPK8(Mitogen-activated protein kinase 8) is also named as JNK1,PRKM8,SAPK1,SAPK1C and belongs to the MAP kinase subfamily. MAPK8 is activated by dual phosphorylation at a Thr-Pro-Tyr motif during response to UV light. MAPK8 functions to phosphorylate c-Jun at N-terminal serine regulatory sites of Ser-63 and Ser-73,mapping within the transactivation domain. Phosphorylation of these sites in response to UV results in transcriptional activation of c-Jun. It has 4 isoforms produced by alternative splicing with the molecular weight of 46 kDa and 48 kDa. This protein can be phosphorylated and this antibody recognizes the 46 kDa and 55 kDa bands in western blot.
- Molecular Weight
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Observed_MW: 46/54kDa
Calculated_MW: 48/53kDa
- Gene ID
- 5599
- UniProt
- P45983
- Pathways
- MAPK Signaling, WNT Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, S100 Proteins
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