HRAS antibody

Catalog No. ABIN7384449

The Rabbit Monoclonal anti-HRAS antibody is suitable to detect HRAS in samples from Human, Mouse, Rat and Hamster. It has been validated for WB.

Quick Overview for HRAS antibody (ABIN7384449)

Target: HRAS (HRas proto-oncogene, GTPase (HRAS))

Reactivity: Human, Mouse, Rat, Hamster

Host: Rabbit

Clonality: Monoclonal

Conjugate: This HRAS antibody is un-conjugated

Application: Western Blotting (WB)

Clone: R01-7D0

Product Details anti-HRAS Antibody

Purification: Affinity Purified

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000

Restrictions: For Research Use only

Handling

Concentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for HRAS

Target: HRAS (HRas proto-oncogene, GTPase (HRAS))

Alternative Name: GTPase HRAS

Background: ALPS4,AV095280,GTPase NRas,HRAS1,N ras,N ras protein part 4,Neuroblastoma RAS viral (v ras) oncogene homolog,NRAS,NRAS1,NS6,OTTHUMP00000013879,OTTMUSP00000023521,RASN,Transforming protein N Ras,Transforming protein N-Ras,v ras neuroblastoma RAS viral oncogene homolog,This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. 

Molecular Weight:

Observed_MW: 21kDa

Calculated_MW: 21kDa

Gene ID: 3265, 3845, 4893

UniProt: P01111

Pathways: p53 Signaling, MAPK Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Autophagy, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling, BCR Signaling