Caspase 1 antibody

Catalog No. ABIN7384556

Product Details anti-Caspase 1 Antibody

Target: Caspase 1 (CASP1)

Reactivity: Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caspase 1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Antigen Affinity Purification

Immunogen: Synthetic peptide corresponding to Zebrafish caspase-1 conjugated to keyhole limpet haemocyanin.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-2000, IP: 3 μg/sample, IF: 1:100-200

Restrictions: For Research Use only

Handling

Concentration: 5 mg/mL

Buffer: PBS with 0.1 % sodium azide, 50 % glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Caspase 1

Target: Caspase 1 (CASP1)

Alternative Name: Caspase-1 (CASP1 Products)

Synonyms: ICE antibody, IL1BC antibody, P45 antibody, Il1bc antibody, Ice antibody, CASP1 antibody, CG5370 antibody, DCP-1 antibody, DCP1 antibody, Dcp1 antibody, Dmel\\CG5370 antibody, ccp1 antibody, dcp-1 antibody, dcp1 antibody, l(2)01862 antibody, l(2)02132 antibody, caspase 1 antibody, caspase 1, apoptosis-related cysteine peptidase antibody, caspase 4, apoptosis-related cysteine peptidase antibody, Death caspase-1 antibody, caspase-1 antibody, caspase antibody, caspase recruitment domain-containing protein 16 antibody, caspase 4 antibody, CASP1 antibody, Casp1 antibody, CASP4 antibody, Dcp-1 antibody, Caspase1 antibody, LOC5564196 antibody, LOC451519 antibody

Background: CASP1,ICE,IL1BC,P45,caspase-1,Caspase 1,CASP1(caspase-1) is also named as IL1BC, IL1BCE and belongs to the peptidase C14A family. It is a cysteine protease that regulates inflammatory processes through its capacity to process and activate the interleukin-1-beta (IL1B), IL18, and IL33 precursor

Molecular Weight:

Observed_MW: 20kDa,42kDa

Calculated_MW: 45, 42, 35, 22, 20kDa

Gene ID: 57933

UniProt: Q9I9L7

Pathways: Apoptosis, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome