TNRC6A antibody (AA 575-625)

Catalog No. ABIN7459937

Product Details anti-TNRC6A Antibody

Target: TNRC6A (Trinucleotide Repeat Containing 6A (TNRC6A))

Binding Specificity: AA 575-625

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNRC6A antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Rabbit anti-GW182 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 575 and 625

Isotype: IgG

Application Details

Application Notes:

IP: 6 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for TNRC6A

Target: TNRC6A (Trinucleotide Repeat Containing 6A (TNRC6A))

Alternative Name: GW182 (TNRC6A Products)

Synonyms: 2010321I05Rik antibody, 3110054G10Rik antibody, AW557223 antibody, CAGH26 antibody, D130023A07Rik antibody, GW182 antibody, Tnrc6 antibody, GW1 antibody, TNRC6 antibody, trinucleotide repeat containing 6a antibody, trinucleotide repeat containing 6A antibody, Tnrc6a antibody, TNRC6A antibody

Background: Background: GW182 (glycine-tryptophan protein of 182 kDa) is a member of the trinucleotide repeat containing 6 protein family. It functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. GW182 has been found to associate with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibition of GW182 expression delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing [taken from NCBI GeneID:27327].

Gene ID: 27327

NCBI Accession: NP_055309

UniProt: Q8NDV7